儿童骨与关节感染的临床表现和治疗效果

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL Cukurova Medical Journal Pub Date : 2023-10-16 DOI:10.17826/cumj.1348227
Melis Deniz, Tuğba Erat, A. Yavuz, Kazım Tasar
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引用次数: 0

摘要

目的:本研究旨在确定儿童骨与关节感染的临床、实验室、影像学和细菌学特征,并找出其早期诊断的特征。 材料与方法:在这项回顾性研究中,纳入了根据既定指南诊断为骨髓炎和化脓性关节炎的患者。我们收集了人口统计学、临床和影像学数据、炎症标志物和微生物学数据,以及骨科医生实施的任何侵入性手术。我们还审查了长期后遗症的发展情况、治疗持续时间以及口服和肠外治疗所用抗生素的类型。 研究结果研究组包括 25 名骨髓炎患者、10 名化脓性关节炎患者和 5 名合并感染(骨髓炎和化脓性关节炎)患者。大多数患儿的炎症标志物水平异常。最常见的病原体是葡萄球菌。在所有有磁共振成像结果的患者中,都发现了与骨和关节感染相符的放射学结果。分别有44%、90%和100%的骨髓炎、化脓性关节炎和合并感染患者接受了侵入性治疗。 结论是同时使用所有标记物时,灵敏度会提高。在我们的研究中,磁共振成像被认为是对骨和关节感染最有参考价值的成像方式,其灵敏度最高。这些敏感指标有助于对表现不明确的患者进行早期诊断和长期随访。
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Kemik ve eklem enfeksiyonları olan çocukların klinik bulguları ve sonuçları
Purpose: This study aimed to determine the clinical, laboratory, imaging, and bacteriological features of bone and joint infections in children and to identify their characteristic features for early diagnosis. Materials and Methods: In this retrospective study patients diagnosed with osteomyelitis and septic arthritis, based on established guidelines, were included. We collected demographic, clinical, and imaging data, along with inflammatory markers and microbiological data, and any invasive procedures performed by orthopedic surgeons. We also reviewed the development of long-term sequelae, the duration of treatments, and the types of antibiotics used for both oral and parenteral therapy. Results: The study group consisted of 25 patients with osteomyelitis, 10 with septic arthritis, and 5 with combined infection (osteomyelitis and septic arthritis). Inflammatory marker levels were abnormal in most children. The most commonly identified organism was the Staphylococcal species. Radiological findings compatible with bone and joint infections were detected in all patients whose magnetic resonance imaging results were available. Invasive procedures were performed in 44%, 90%, and 100% of the patients with osteomyelitis, septic arthritis, and combined infection, respectively. Conclusion: Sensitivity increased when all the markers were used together. Magnetic resonance imaging considered the most informative imaging modality for bone and joint infections provided the highest sensitivity in our study. These sensitive indicators can be helpful for the early diagnosis and long-term follow-up of patients with unclear presentations.
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来源期刊
Cukurova Medical Journal
Cukurova Medical Journal MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
159
审稿时长
12 weeks
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