评估从不同果皮中提取的基于纳米颗粒的凝胶

Kanwar Madhu, Choudhary Suresh
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引用次数: 0

摘要

纳米粒子是指大小在 1 纳米到 100 纳米之间的颗粒。三角形、球形、不规则形状等。它们有不同的尺寸,例如近年来,纳米粒子的合成因其独特的性质和潜在的应用而受到广泛关注。粉末样品(100 克)用 800 毫升乙醇以索氏提取法提取 6 小时。提取物用于制备纳米颗粒。本研究的主要目的是通过化学络合法制备基于青苹果和橙皮提取物的纳米颗粒。使用索氏提取器制备了青苹果和橘子皮的乙醇提取物,并对其植物化学成分进行了分析。青苹果皮的定性分析结果显示生物碱、蒽醌类、皂苷和萜类化合物呈阳性,而橘子皮则呈阳性。生物碱、单宁和皂苷的结果良好。两种水果(青苹果和橙子)的水分百分比分别为 72% 和 96.12%。青苹果和橙子的 pH 值分别为 3.6 和 3.8。青苹果提取物纳米粒子的 zeta 电位为 -24.6 mV 至 -34.5 mV(P20 和 P50),橙子提取物的 zeta 电位为 -21.4 mV 至 32.0 mV(O20 和 O50)。对于纳米颗粒来说,这些值更高,表明聚集的可能性更小。苹果提取物的粒度从 118.6 纳米到 231.7 纳米不等(P20 和 P30),而橙子提取物的粒度从 178.8 纳米到 191.6 纳米不等(O20 和 O50)。这条线证实了所获得的颗粒在纳米范围内,即尺寸小于 500 纳米。扫描电子显微镜(SEM)结果显示形成了纳米颗粒,其形状为球形。能量色散光谱(EDS)分析证实了纳米银粒子的存在。银纳米粒子是用绿果皮和橙汁皮制备的。可计算性研究 FT-IR 表明,制备的纳米粒子外壳的官能团没有变化。Zeta 电位表明颗粒的效率较高,因此聚集较少。制备的纳米粒子呈球形,粒径约为 200 ± 20 纳米。该研究将进一步扩展到抗微生物和伤口愈合活性方面。关键词: 橙皮提取物 定性分析 纳米颗粒 Zeta 电位 颗粒大小
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EVALUATION OF NANOPARTICLES BASED GELS FROM EXTRACTION OF DIFFERENT FRUIT PEELS
Nanoparticles are particles ranging in size from 1 nm to 100 nm. Triangles, spheres, irregular shapes, etc. They come in different sizes such as. In recent years, the synthesis of nanoparticles has received widespread attention due to their unique properties and potential applications. The powder sample (100gm) was extracted with 800ml ethanol using Soxhlet extraction method for 6 hours. The resulting extract is used in the preparation of nanoparticles. The main objective of the present work was to prepare green apple and orange peel extract based nano particles by chemical complexation method. Ethanol extracts of green apple and orange peel were prepared using Soxhlet extractor and analyzed for their phytochemical composition. qualitative analysis of green apple peel showed positive results for alkaloids, anthraquinones, saponins and terpenoids, while orange peel showed positive. Good results for alkaloids, tannins and saponins. The moisture percentage of two fruits (green apple and orange) is 72% and 96.12% respectively. Green apples and oranges have a pH of 3.6 and 3.8 respectively. The zeta potential of green apple extract nanoparticles is -24.6 mV to -34.5 mV (P20 and P50), and the zeta potential of orange extract is -21.4 mV to 32.0 mV (O20 and O50). For nanoparticles these values are higher, indicating less potential for aggregation. The size of the apple extract varies from 118.6 nm to 231.7 nm (P20 and P30), while the size of the orange extract varies from 178.8 nm to 191.6 nm (O20 and O50). This line confirms that the obtained particles are in the nanometer range, i.e. <500 nm in size. SEM results show the formation of nanoparticles and their shape is spherical. Energy dispersive spectroscopy (EDS) analysis confirmed the presence of silver nanoparticles. Silver nanoparticles were prepared using green and orange juice peels. Computability studies FT-IR showed that there was no change in the functional group of the shell in the prepared nanoparticles. Zeta potential indicates higher efficiency and therefore less particle aggregation. The prepared nanoparticles are spherical in shape and have a particle size of approximately 200 ± 20nm. Further the study will be extended for anti- microbial and wound healing activities. KEYWORDS: Orange peel extract, Qualitative analysis, Nano particles, Zeta potential, Particle Size
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