急性 ST 段抬高型心肌梗死中桡动脉和股动脉入路的比较研究;即时和短期随访

Tamim Abo El-Naga, A. Harfoush, M. Sallam
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摘要

背景:经桡动脉入路(TRA)作为经股动脉入路(TFA)的替代方法已被广泛接受,但仍存在血肿、痉挛和桡动脉闭塞等诸多隐患。目的评估在 ST 段抬高型心肌梗死(STEMI)患者中使用 TRA 与 TFA 相比进行冠状动脉造影(CAG)和经皮冠状动脉介入治疗(PCI)的可行性和安全性。研究方法我们的研究是一项前瞻性分析,连续纳入了 100 名急性 STEMI 患者。这些患者被随机分配到从 TFA(I 组,50 名患者)或 TRA(II 组,50 名患者)获得血管通路。收集临床、技术、程序和术后数据。结果显示第一组比第二组年轻(53.0±8.4)岁对(55.8±10.9)岁,但没有统计学意义(P= 0.156)。既往有 STEMI 病史的患者明显多于 II 组(6% 对 16%,P=0.032)。在手术成功率(98% 对 96%)和固定股骨或桡骨鞘的尝试次数方面,两组之间没有差异。然而,桡动脉组的手术总时间、造影剂用量和透视时间分别显著高于股动脉组(42.2 ± 16.8 分钟对 77.4 ± 27.1 分钟)、(157.4 ± 10.8 毫升对 181.2 ± 16.7 毫升)和(8.74 ± 3.8 分钟对 18.64 ± 7.1 分钟),P=0.001。两组发生急性并发症的频率相似,尽管第二组血肿较少,但未达到统计学意义。结论我们的研究表明,与股动脉入路相比,桡动脉入路是对 ST 段抬高型心肌梗死患者进行冠状动脉造影或血管成形术的一种安全实用的方法,且无重大并发症,但手术时间明显更长,造影剂用量和透视时间也更长。
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COMPARATIVE STUDY BETWEEN RADIAL AND FEMORAL ARTERY APPROACHES IN ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; IMMEDIATE AND SHORT-TERM FOLLOW UP
Background: Trans-radial approach (TRA) gained sound acceptance as an alternative to trans-femoral approach (TFA), however, still having numerous pitfalls as hematoma, spasm and radial artery occlusion. Objectives: To evaluate the feasibility and safety of TRA for coronary angiography (CAG) and percutaneous coronary intervention (PCI) compared with the TFA in ST segment elevation myocardial infarction (STEMI) patients. Methods: Our study was a prospective analysis enrolled 100 consecutive patients presented with acute STEMI. The patients were randomly assigned to get vascular access either from TFA (Group I, 50 patients) or from TRA (Group II, 50 patients). The clinical, technical, procedural and post-procedural data collected. Results: Group I was younger than Group II (53.0±8.4) versus (55.8±10.9 years), however didn’t reach a statistical significance (p= 0.156). History of prior STEMI was significantly more in group II (6% versus 16%, p=0.032). There was no difference between the two groups regarding the procedural success (98% versus 96%) and number of attempts to fix the femoral or radial sheath. However, the total procedure time, amount of contrast usage and fluoroscopic time were significantly higher in radial group (42.2 ± 16.8 versus 77.4 ± 27.1 minutes), (157.4 ± 10.8 versus 181.2 ± 16.7 milliliter) and 8.74 ± 3.8 versus 18.64 ± 7.1 minute) with p=0.001 respectively. The frequency of acute complications was similar in both groups despite hematoma was less in group II, however, it didn’t reach statistical significance. Conclusions: Our study demonstrated the radial access is a safe and practical approach for coronary angiography or angioplasty in ST segment elevation myocardial infarction patients compared to femoral access, without major complications, however, the procedure time was significantly longer with higher usage of contrast media and fluoroscopic time.
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