Changes in Optical Coherence Tomography Angiography after Suprachoroidal Triamcinolone Acetonide injection in Diabetic patients

Background: Diabetic macular edema (DME) is a leading cause for loss of central vision in diabetics with retinopathy. Treatment approaches for DME have shifted away from Laser therapy as the first line of therapy for DME. Aim and objectives: to investigate the changes in Optical coherence tomography angiography (OCT-A) after suprachoroidal injection of triamcinolone acetonide (SCTA) in patients with diabetic macular edema. Patients and Methods: This a prospective case series study that was conducted on twenty eyes with refractory diabetic macular edema who treated with single suprachoroidal injection of triamcinolone acetonide. All patients underwent history taking, ocular examination and optical coherence tomography angiography (OCT-Angiography). Results: there was no statistically significant difference between the studied groups as regard (Relation between baseline, third month and sixth month LogMAR BCVA), (Relation between baseline, third month and sixth month CFT (Central foveal thickness)), (Relation between baseline, third month, sixth month SVD (superficial vessel density) and sixth month DVD (Deep vessel density)), (Relation between baseline, third month and sixth month FAZ (Foveal avascular zone) in mm) and (Correlation between BCVA at six month and (CFT, SVD, DVD, FAZ) at six months). Conclusion: our findings suggest that SCTA may be an effective treatment option for diabetic macular edema, improving visual outcomes and reducing retinal thickness.