没食子酸作为最终冲洗剂对环氧树脂封闭剂与根管牙本质的推出粘接强度的影响

Q3 Pharmacology, Toxicology and Pharmaceutics Journal of HerbMed Pharmacology Pub Date : 2023-08-10 DOI:10.34172/jhp.2023.44919
Sarath Kumar, Kavitha Sanjeev, Nagarathinam Sundaramoorthy, S. Mahalaxmi
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引用次数: 0

摘要

简介:乙二胺四乙酸(EDTA)是一种广泛使用的螯合剂,在用作最后冲洗溶液时会影响树脂封闭剂的粘接强度。因此,我们分析了在使用没食子酸(一种螯合剂)作为最后冲洗液时,树脂基封闭剂 AH Plus 的推出粘接强度。研究方法取 40 颗人类单根牙齿,随机分为 4 组(n = 10):EA(17% EDTA)、MA(7% 马来酸)、GA(10% 没食子酸)和 SA(生理盐水)。灌洗后,在根管上涂抹 AH Plus 封闭剂,并使用古塔波卡堵塞根管。将根管水平分为冠状、中间和根尖三部分,以评估推出粘接强度。使用压缩负荷为 1 毫米/分钟的万能试验机对样品进行测试。结果:与 EA 和 SA 相比,GA 在冠状三分之一处的推出粘接强度有所提高,但与 MA 相比并不显著(P > 0.05)。在中间三分之一处也观察到类似的情况,但与所有其他组相比,差异有统计学意义(P < 0.05)。此外,各组在顶端三分之一处的差异也不显著。与实验组相比,SA 显示出最低的推出粘接强度,这在所有三个部分都有显著性差异(P < 0.05)。结论10% 没食子酸的最后冲洗提高了 AH Plus 在根管所有三分之一处与根牙本质的推出粘接强度。因此,10% 没食子酸可能是替代合成螯合剂的有效方法。
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Effect of gallic acid as a final irrigant on push-out bond strength of an epoxy resin sealer to root canal dentin
Introduction: Ethylenediaminetetraacetic acid (EDTA), a widely used chelating agent, compromises the bond strength of resin-based sealers when used as a final irrigating solution. Hence, the push-out bond strength of AH Plus, a resin-based sealer, was analyzed when gallic acid, "a chelator" was used as a last irrigating solution. Methods: Forty human single-rooted teeth were accessed and randomly assigned into 4 groups (n = 10): EA (17% EDTA), MA (7% maleic acid), GA (10% gallic acid), and SA (saline). After irrigation, the root canals were coated with AH Plus sealer and obturated using gutta-percha. The root canals were sectioned horizontally into coronal, middle, and apical thirds for evaluating the push-out bond strength. A universal testing machine with a compressive loading of 1 mm/min was employed to test the samples. Results: An increased push-out bond strength was noted with GA in coronal one-third compared to EA and SA but not significant compared to MA (P > 0.05). Similar observations were seen in the middle one-third; however, it was statistically significant compared to all other groups (P < 0.05). Also, the difference between the groups in the apical one-third was not significant. SA showed the lowest push-out bond strength than experimental groups, which was significant in all three sections (P < 0.05). Conclusion: The final rinse of 10% gallic acid increased the push-out bond strength of AH Plus to the root dentin in all thirds of the root canal. Hence, gallic acid 10% might be an effective alternative solution in place of synthetic chelators.
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来源期刊
Journal of HerbMed Pharmacology
Journal of HerbMed Pharmacology Pharmacology, Toxicology and Pharmaceutics-Drug Discovery
CiteScore
2.50
自引率
0.00%
发文量
49
审稿时长
12 weeks
期刊介绍: Journal of Herbmed Pharmacology (J Herbmed Pharmacol) is the intersection between medicinal plants and pharmacology. This international journal publishes manuscripts in the fields of medicinal plants, pharmacology and therapeutic. This journal aims to reach all relevant national and international medical institutions and persons in electronic version free of charge. J Herbmed Pharmacol has pursued this aim through publishing editorials, original research articles, reviews, mini-reviews, commentaries, letters to the editor, hypothesis, case reports, epidemiology and prevention, news and views. In this journal, particular emphasis is given to research, both experimental and clinical, aimed at protection/prevention of diseases. A further aim of this journal is to emphasize and strengthen the link between herbalists and pharmacologists. In addition, J Herbmed Pharmacol welcomes basic biomedical as well as pharmaceutical scientific research applied to clinical pharmacology. Contributions in any of these formats are invited for editorial consideration following peer review by at least two experts in the field.
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