在 XRD 研究之前从粘性和非挥发性溶剂中清洗重结晶药物的简单策略:技术说明

E. Rahimpour, A. Jouyban
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引用次数: 0

摘要

目的:从粘性和非挥发性溶剂中获取干燥粉末残留物是不可能的。因此,使用干燥材料所需的方法对其进行分析一直是个问题。在本技术说明中,我们的目的是针对这一问题提供一种简单的方法。结果:所建议的方法是用挥发性溶剂清洗粘性残留物,然后在环境条件下将其干燥。为此,我们提供了一些药物在选定的粘性和非挥发性溶剂中的充分数据,以支持我们的主张。
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A simple strategy for washing a recrystallized drug from viscous and non-volatile solvents prior to XRD study: A technical note
Aim: obtaining a dried powder residual from a viscous and non-volatile solvents isimpossible. Thus, their analysis by using the methods required for the dried formof materials has always been a problem. In the current technical note, our aim wasto offer a simple method for this issue. Results: the proposed method was basedon washing of the viscous residuals with a volatile solvent and their drying in theambient conditions. For this purpose, we have provided sufficient data on somedrugs in the selected viscous and non-volatile solvents to support our claim.
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