COVID-19: Two years in the history and still a mystery! A case series of three interesting cases

COVID-19 was first identified as a new disease in December 2019. It’s now more than 2 years since its discovery and much research has been done. Still, there are some aspects in the pathogenesis and management that have not been completely understood. The cornerstone of therapy lies in the supportive treatment to maintain oxygenation. To the best of our knowledge, there are no earlier reports of severe COVID-19 with respiratory failure that have recovered without supplemental oxygen therapy. We present three unique cases of severe COVID-19 who were managed at home despite hypoxemia. The scarcity of oxygen during the second wave in Delhi deprived them of essential oxygen therapy. The patients survived and recovered well. Happy hypoxemia and hypoxic preconditioning played their role in symptoms tolerance. Therapeutically, the role of awake proning and steroid in the management cannot be undermined. Lastly, the technology in terms of video consultation definitely was useful in allaying the anxiety and guiding the right treatment.