南印度女性人口中艾滋病毒感染率的估计:贝叶斯方法

Elangovan Arumugum, Vasna Joshua
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引用次数: 0

摘要

导言:国家艾滋病控制组织(NACO)开展的艾滋病毒哨点监测(HSS)是印度估算艾滋病毒感染率的主要数据来源。HSS 针对的是有感染 HIV 风险的主要人群,而全国家庭健康调查(NFHS)测量的是基于社区的 HIV 感染率。根据从 NACO-HSS 和 NFHS 中获得的 HIV 感染率数据,对印度的 HIV 感染率进行了改进估计。方法:采用贝叶斯分析法确定了印度南部七个邦的女性艾滋病毒流行率。分析包括绘制先验分布、似然分布和后验分布图,以便对数据进行直观评估。先验分布使用的是根据 NFHS(2015-16 年)调查数据计算得出的女性艾滋病毒感染率。从 2019 年艾滋病毒哨点监测中获得的孕妇艾滋病毒感染率用于似然。贝叶斯分析使用 R 编程(RStudio 2022.02.0)进行。通过应用贝叶斯定理,利用先验分布和似然得到后验概率分布。通过 R 的绘图功能实现了图形表示。由于 NFHS 和 HSS 报告的流行率为零或非常低,因此喀拉拉邦和本迪榭里未纳入分析。结果安得拉邦女性艾滋病感染率的贝叶斯估计值为 0.38 % [95% CI:0.29 - 0.47],卡纳塔克邦为 0.28 [95% CI:0.23 - 0.35],奥迪沙邦为 0.27 [95% CI:0.20 - 0.34],特兰甘纳邦为 0.27 % [95% CI:0.19 - 0.36],泰米尔纳德邦为 0.19 [95% CI:0.15 - 0.24]。结论贝叶斯技术是建立模型和分析 HIV 相关数据的一种灵活而强大的策略,为数据分析提供了一种灵活而强大的方法。
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Estimation of HIV Prevalence among the Female Population in South India: A Bayesian Approach
Introduction: The HIV Sentinel Surveillance (HSS) conducted by National AIDS Control Organization (NACO) is the predominant data source for HIV estimations in India. While the HSS targets the key populations at risk of HIV infection, the National Family Health Survey (NFHS) measures the community- based HIV prevalence. Improvised HIV estimates in India were attributed to the HIV prevalence data obtained from the NACO-HSS and NFHS. Methods: Bayesian analysis was performed to determine the state-level prevalence of HIV among females in seven South Indian States. The analysis involved plotting the prior, likelihood, and posterior distributions, facilitating a visual assessment of the data. The HIV prevalence among females calculated from the NFHS (2015-16) survey data was used for prior distributions. HIV prevalence among pregnant women obtained from the HIV Sentinel Surveillance 2019 was used for likelihood. Bayesian analysis was performed using the R programming (RStudio 2022.02.0). A posterior probability distribution was obtained using the prior distribution and the likelihood by applying the Bayes theorem. Graphical representation was achieved through R's plotting functions. Kerala and Pondicherry were not included in the analysis due to zero or very low prevalence reported in both NFHS and HSS. Results: The Bayesian estimates of HIV prevalence among females were 0.38 % [95% CI:0.29 - 0.47] in Andhra Pradesh, 0.28 [95% CI:0.23 - 0.35] in Karnataka, 0.27 [95% CI:0.20 - 0.34] Odisha, 0.27 % [95% CI:0.19 - 0.36] in Telangana and 0.19 [95% CI:0.15 - 0.24] in Tamil Nadu. Conclusion: Bayesian techniques present a versatile and robust strategy for modelling and analysing HIV- related data, offering a flexible and powerful approach to data analysis.
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