数字式自我报告 G8 筛查工具:对比研究

Trina Arifin, W. Ong, Yu Ling Juliana Chia, Agnes Lai Yin Chow, Anupama Roy Chowdhury, Johan Chan, Wei Chong Tan, M. B. Ramalingam, T. Rajasekaran, Tira J Tan, L. Krishna, O. Lai, S. Chen, R. Kanesvaran
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摘要

老年评估(GA)已被证明对老年癌症患者的预后至关重要。G8筛查工具可以作为一种潜在的替代工具,在繁忙的肿瘤诊所中识别出哪些患者可以从进一步的老年医学评估中获益,而数字版的G8筛查工具则可以得到更广泛的应用。开发数字版自我报告 G8,并将其结果与医护人员亲自进行的 G8 进行比较。我们分析了在新加坡国立癌症中心(NCCS)诊所接受现场 G8 评估的 483 名 70 岁及以上癌症患者,以及完成数字自我报告 G8 的另外 544 名患者。G8总分≤14分为阳性筛查。数字自报 G8 的响应率为 50%。在线筛查者的 G8 总分中位数低于亲自筛查者(11 分 vs 12.5 分,p < 0.001)。在多变量逻辑回归分析中,在线筛查者的 G8 阳性几率高于亲自筛查者(几率比 = 1.56,95% CI 1.08-2.26)。约有 20 名亲自筛查者也完成了数字自我报告 G8,他们的亲自和在线 G8 总分之间的一致性很高(一致性相关系数 = 0.798,95% CI 0.635-0.962)。数字自我报告 G8 是可行的。不过,鉴于在线筛查者的阳性筛查率较高,只有在获得更多关于现场和在线 G8 分数一致性的确凿证据后,才能用数字自我报告 G8 取代现场 G8。
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A digital self-reported G8 screening tool: A comparison study
Geriatric assessment (GA) has been shown to be pivotal to the prognosis of elderly cancer patients. A G8 screening tool could act as a potential surrogate to identify patients who would benefit from further GA in a busy oncology clinic and a digital version would allow for a wider application. To develop a digital self-reported version of G8, and to compare its outcomes with in-person G8 administered by a healthcare professional. A total of 483 cancer patients aged 70 years and older who received an in-person G8 assessment at the National Cancer Centre Singapore (NCCS) clinic, and another 544 who completed the digital self-reported G8 were analysed. Total G8 score ≤14 was defined as positive screen. Response rate of the digital self-reported G8 was 50%. Median G8 total score was lower among online screeners than in-person screeners (11 vs 12.5, p < 0.001). The odds of a G8 positive screen among online screeners was higher than that of in-person screeners on multivariable logistic regression analysis (odds ratio = 1.56, 95% CI 1.08-2.26). Some 20 in-person screeners had also completed the digital self-reported G8, and the agreement between their in-person and online G8 total scores was high (concordance correlation coefficient = 0.798, 95% CI 0.635-0.962). A digital self-reported G8 is feasible. However, given the higher positive screen rate among the online screeners, replacement of the in-person G8 with the digital self-reported G8 should be implemented only after more conclusive evidence on the agreement between in-person and online G8 score is available.
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