前列腺癌抢救性冷冻疗法

IF 1.4 Q3 UROLOGY & NEPHROLOGY Archivio Italiano di Urologia e Andrologia Pub Date : 2024-01-08 DOI:10.4081/aiua.2023.11897
Duarte Vieira E Brito, Jose Alberto Pereira, Ana Maria Ferreira, Mario Lourenço, Ricardo Godinho, Bruno Pereira, Pedro Peralta, Paulo Conceiçao, Mario Reis, Carlos Rabaça
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引用次数: 0

摘要

背景:大多数被诊断出患有前列腺癌的男性都有可能接受积极治疗,而在采用保留器官策略治疗的患者中,有20%到50%的患者会在前列腺内复发。复发的最佳治疗方法尚存争议。前列腺冷冻手术已越来越多地被用作前列腺癌的初治、复发和病灶治疗:我们分析了 55 例复发后接受冷冻治疗作为挽救治疗的患者:研究对象的平均年龄为(70.9 ± 6.2)岁,最初的平均前列腺特异性抗原(PSA)为 7.6 ng/ml,超声检查的平均前列腺体积为(43.2 ± 14.7)克。平均随访时间为 18.0 个月。随访一年后的无生化生存率为 85%:结论:冷冻疗法是治疗原发性根治失败后复发的一种有效而安全的方法。
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Salvage cryotherapy for prostate cancer.

Background: Most men diagnosed with prostate cancer will be candidates for active treatment and 20 to 50% of patients treated with organ preserving strategies recur within the prostate. Optimal treatment of recurrence is controversial. Prostate cryosurgery has been increasingly used as primary, recurrence and focal treatment for prostate cancer.

Methods: We analysed 55 patients submitted to cryotherapy as salvage treatment after recurrence.

Results: Study population presented with a mean age of 70.9 ± 6.2 years, mean initial PSA of 7.6 ng/ml and average prostate volume by ultrasound of 43.2 ± 14.7 grams. Mean follow-up was of 18.0 months. Biochemical free survival at one year of follow-up was of 85%.

Conclusions: Cryotherapy can be an effective and safe treatment for recurrence after primary curative treatment failure.

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来源期刊
CiteScore
2.10
自引率
35.70%
发文量
72
审稿时长
10 weeks
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