采用不同能量方案的微脉冲二极管激光经巩膜环形光凝术的疗效比较

IF 1 Q4 OPHTHALMOLOGY Taiwan Journal of Ophthalmology Pub Date : 2024-01-05 DOI:10.4103/tjo.tjo-d-23-00129
Kuan-Yu Chen, Shirley H. L. Chang
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引用次数: 0

摘要

本研究旨在探讨微脉冲经巩膜环形光凝治疗青光眼患者激光治疗设置的安全性和有效性,并评估眼压降低与不同治疗参数之间的关系。 研究共纳入了 64 名青光眼患者中的 74 只眼睛,这些患者的眼压超过 21 mmHg 或低于 20 mmHg,并伴有视野恶化,他们都接受了微脉冲经巩膜环形光凝治疗。以眼压降低率达到 20% 为标准,将患者分为成功组和失败组。评估了成功组和失败组眼压降低的预测因素以及不同治疗时间组的眼压降低率。采用单变量和多变量回归模型对眼压降低的预测因素进行了分析。 成功组患者的基线眼压明显更高(中位数:28.0 对 23.0 mmHg;P = 0.016),治疗时间更长(中位数:240 对 160 秒;P = 0.001)。治疗时间范围在 200 至 240 秒之间的眼压降低率(47.8 ± 17.4%)明显高于治疗时间在 140 秒以下的眼压降低率(23.1 ± 14.2%)。单变量分析表明,基线眼压和治疗持续时间是降低眼压的重要因素。多变量分析进一步表明,治疗时间超过 200 秒是降低眼压的重要预测因素。 在微脉冲环形光凝疗法中,治疗持续时间设置是影响眼压降低率的最重要因素。根据目标眼压降低率进行定制化治疗,可采用不同的治疗持续时间设置,以获得最佳疗效。
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Comparison of the efficacy of micropulse diode laser transscleral cyclophotocoagulation using different energy protocols
This study aimed to explore the safety and efficacy of laser treatment settings of micropulse transscleral cyclophotocoagulation treatment in glaucoma patients and to evaluate the relationship between intraocular pressure (IOP) reduction and different treatment parameters. A total of 74 eyes in 64 glaucoma patients with IOP over 21 mmHg or under 20 mmHg with visual field progression who underwent micropulse transscleral cyclophotocoagulation treatment were included. Patients were divided into success and failure groups based on criteria of 20% IOP reduction rate. The predictive factors of IOP reduction between success and failure groups and the IOP reduction rates in the different treatment duration groups were evaluated. Predictive factors for IOP reduction were analyzed using univariate and multivariate regression models. Patients in the success group had significantly higher baseline IOP (median: 28.0 vs. 23.0 mmHg; P = 0.016) and longer treatment times (median: 240 vs. 160 s; P = 0.001). Treatment duration range between 200 and 240 s achieved significantly higher intraocular pressure reduction rates (47.8 ± 17.4%) than durations under 140 s (23.1 ± 14.2%). Univariate analysis showed that baseline IOP and treatment duration were significant contributing factors in IOP reduction. Multivariable analysis further demonstrated that treatment duration over 200 s was the significant predictive factor for IOP reduction. Treatment duration settings were the most significant factor of IOP reduction rates in micropulse cyclophotocoagulation. Customized therapy according to the target IOP reduction rate can be applied with different treatment duration settings to achieve optimal outcomes.
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来源期刊
CiteScore
1.80
自引率
9.10%
发文量
68
审稿时长
19 weeks
期刊最新文献
Advancing glaucoma care with big data and artificial intelligence innovations. Application of artificial intelligence in glaucoma care: An updated review. Artificial intelligence and big data integration in anterior segment imaging for glaucoma. Big data and electronic health records for glaucoma research. Big data for imaging assessment in glaucoma.
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