A. Dudhe, R. Dudhe, Renuka Mahajan, Neha Pathak, Vaibhav Uplanchiwar, Mohammad Hashim Mansoori
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Wide-ranging Study on Synthesis and Biological Evaluation of 1, 2, 3-Triazole
1, 2, 3-Traizole is five-membered heterocyclic compounds having three nitrogen at 1, 2
and 3 positions. 1, 2, 3-Triazoles are important five-membered heterocyclic scaffolds due to their
widespread biological activities. 1, 2, 3-Triazole derivative can be readily obtained in good to
excellent yields through click chemistry, 1, 3-dipolar cycloaddition, Metal Catalysed azide-alyne
cycloaddition method. 1, 2, 3-Triazoles showed various biological activities, such as antiinflammatory, anticonvulsant, antineoplastic, antimicrobial, analgesic, antimalarial, antiviral, antiproliferative, and anticancer activities. The objective of this review is to synthesize pharmacological activity of 1,2,3-triazole derivatives documented in recent literature.
Current Bioactive CompoundsPharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.90
自引率
0.00%
发文量
112
期刊介绍:
The journal aims to provide comprehensive review articles on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.