J.J. Raposo-López, M.S. Tapia-Sanchiz, V. Navas-Moreno, J.A. Arranz Martín, M. Marazuela, F. Sebastián-Valles
{"title":"剩余胆固醇与 1 型糖尿病患者血糖控制程度和微血管并发症的关系。","authors":"J.J. Raposo-López, M.S. Tapia-Sanchiz, V. Navas-Moreno, J.A. Arranz Martín, M. Marazuela, F. Sebastián-Valles","doi":"10.1016/j.rce.2023.11.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>This study examines the relationship between remnant cholesterol, glucose metrics, and chronic complications of type 1 diabetes in users of glucose monitoring systems.</p></div><div><h3>Material and methods</h3><p>Clinical variables and glucose metrics were collected from individuals using glucose sensors. Statistical models were employed to investigate the association of remnant cholesterol with glucose metrics, diabetic retinopathy, and diabetic nephropathy.</p></div><div><h3>Results</h3><p>A total of 383 individuals, aged 48.3<!--> <!-->±<!--> <!-->16.2 years, with 54.1% women, and a remnant cholesterol level of 16<!--> <!-->±<!--> <!-->10<!--> <!-->mg/dL, were included. The results demonstrated that remnant cholesterol was associated with less time within the target range (<em>P</em>=.015) and more time above the target range (<em>P</em>=.003). Diabetic nephropathy was the only complication associated with remnant cholesterol levels exceeding 30<!--> <!-->mg/dL; OR: 8.93; 95% CI: 2.99-26.62, <em>P</em><.001.</p></div><div><h3>Conclusion</h3><p>Remnant cholesterol is independently associated with hyperglycemia and diabetic nephropathy in individuals with type 1 diabetes.</p></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0014256523001935/pdfft?md5=c05f415116a38679e18801cacd2d4bcd&pid=1-s2.0-S0014256523001935-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Asociación del colesterol remanente con el grado de control glucémico y la presencia de complicaciones microvasculares en personas con diabetes mellitus tipo 1\",\"authors\":\"J.J. Raposo-López, M.S. Tapia-Sanchiz, V. Navas-Moreno, J.A. Arranz Martín, M. Marazuela, F. Sebastián-Valles\",\"doi\":\"10.1016/j.rce.2023.11.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>This study examines the relationship between remnant cholesterol, glucose metrics, and chronic complications of type 1 diabetes in users of glucose monitoring systems.</p></div><div><h3>Material and methods</h3><p>Clinical variables and glucose metrics were collected from individuals using glucose sensors. Statistical models were employed to investigate the association of remnant cholesterol with glucose metrics, diabetic retinopathy, and diabetic nephropathy.</p></div><div><h3>Results</h3><p>A total of 383 individuals, aged 48.3<!--> <!-->±<!--> <!-->16.2 years, with 54.1% women, and a remnant cholesterol level of 16<!--> <!-->±<!--> <!-->10<!--> <!-->mg/dL, were included. The results demonstrated that remnant cholesterol was associated with less time within the target range (<em>P</em>=.015) and more time above the target range (<em>P</em>=.003). Diabetic nephropathy was the only complication associated with remnant cholesterol levels exceeding 30<!--> <!-->mg/dL; OR: 8.93; 95% CI: 2.99-26.62, <em>P</em><.001.</p></div><div><h3>Conclusion</h3><p>Remnant cholesterol is independently associated with hyperglycemia and diabetic nephropathy in individuals with type 1 diabetes.</p></div>\",\"PeriodicalId\":21223,\"journal\":{\"name\":\"Revista clinica espanola\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S0014256523001935/pdfft?md5=c05f415116a38679e18801cacd2d4bcd&pid=1-s2.0-S0014256523001935-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista clinica espanola\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0014256523001935\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista clinica espanola","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014256523001935","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Asociación del colesterol remanente con el grado de control glucémico y la presencia de complicaciones microvasculares en personas con diabetes mellitus tipo 1
Introduction
This study examines the relationship between remnant cholesterol, glucose metrics, and chronic complications of type 1 diabetes in users of glucose monitoring systems.
Material and methods
Clinical variables and glucose metrics were collected from individuals using glucose sensors. Statistical models were employed to investigate the association of remnant cholesterol with glucose metrics, diabetic retinopathy, and diabetic nephropathy.
Results
A total of 383 individuals, aged 48.3 ± 16.2 years, with 54.1% women, and a remnant cholesterol level of 16 ± 10 mg/dL, were included. The results demonstrated that remnant cholesterol was associated with less time within the target range (P=.015) and more time above the target range (P=.003). Diabetic nephropathy was the only complication associated with remnant cholesterol levels exceeding 30 mg/dL; OR: 8.93; 95% CI: 2.99-26.62, P<.001.
Conclusion
Remnant cholesterol is independently associated with hyperglycemia and diabetic nephropathy in individuals with type 1 diabetes.
期刊介绍：
Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.
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