关于膳食成分和模式与老年性黄斑变性的叙述性综述。

IF 5.1 2区 医学 Q1 NUTRITION & DIETETICS Nutrition Research Reviews Pub Date : 2024-01-15 DOI:10.1017/S0954422424000015
Emine Koçyiğit, Nazlıcan Erdoğan Gövez, Sabriye Arslan, Duygu Ağagündüz
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引用次数: 0

摘要

老年黄斑变性(AMD)是全球老龄人口中最常见的眼部疾病之一。它是 55 岁以上人群失明的主要原因,尤其是在西方工业化国家。AMD的发病率随着年龄的增长而增加,遗传因素和环境影响被认为是导致其发病的原因。在环境因素中,饮食对老年性黄斑变性起着重要作用。本综述探讨了膳食成分、膳食模式与老年性黄斑变性之间的关联。文中讨论了各种营养素、非营养素物质和膳食模式,它们有可能抵消氧化应激和炎症,而氧化应激和炎症是导致老年性黄斑变性的根本机制。人们强调,食用水果、蔬菜、鱼类和海产品、全谷物、橄榄油、坚果和低血糖指数食物有利于降低老年痴呆症的风险。地中海饮食包含了这些元素,可推荐将其作为治疗老年黄斑病变的饮食模式。此外,通过饮食干预和益生菌来调节肠道微生物群也显示出了治疗老年性黄斑变性的前景。
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A narrative review on dietary components and patterns and age-related macular degeneration.

Age-related macular degeneration (AMD) is one of the most prevalent eye diseases among the ageing population worldwide. It is a leading cause of blindness in individuals over 55, particularly in industrialised Western countries. The prevalence of AMD increases with age, and genetic factors and environmental influences are believed to contribute to its development. Among the environmental factors, diet plays a significant role in AMD. This review explores the association between dietary components, dietary patterns and AMD. Various nutrients, non-nutrient substances and dietary models that have the potential to counteract oxidative stress and inflammation, which are underlying mechanisms of AMD, are discussed. Consuming fruits, vegetables, fish and seafood, whole grains, olive oil, nuts and low-glycaemic-index foods has been highlighted as beneficial for reducing the risk of AMD. Adhering to the Mediterranean diet, which encompasses these elements, can be recommended as a dietary pattern for AMD. Furthermore, the modulation of the gut microbiota through dietary interventions and probiotics has shown promise in managing AMD.

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来源期刊
Nutrition Research Reviews
Nutrition Research Reviews 医学-营养学
CiteScore
16.10
自引率
1.80%
发文量
30
期刊介绍: Nutrition Research Reviews offers a comprehensive overview of nutritional science today. By distilling the latest research and linking it to established practice, the journal consistently delivers the widest range of in-depth articles in the field of nutritional science. It presents up-to-date, critical reviews of key topics in nutrition science advancing new concepts and hypotheses that encourage the exchange of fundamental ideas on nutritional well-being in both humans and animals.
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