使用 Octavius 四维模型和剂量-体积直方图四维特征进行脊柱 SBRT 治疗前脊柱柱剂量估算:剂量学分析。

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Medical Physics Pub Date : 2023-10-01 Epub Date: 2023-12-05 DOI:10.4103/jmp.jmp_65_23
Mallikarjuna Adavala, K Chandrasekhar Reddy, Shakambari Sadangi, Kausik Bhattacharya
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引用次数: 0

摘要

目的:本研究旨在利用PTW剂量测定Octavius剂量-体积直方图(DVH)四维(4D)特征,在患者治疗前估算脊柱立体定向体放射治疗(SBRT)的脊柱剂量:研究纳入了 23 名患者,并在 Eclipse 计划系统中使用适用于 TrueBeam STx LINAC 机器的各向异性分析算法 (AAA) 算法(瓦里安医疗系统公司,加利福尼亚州帕洛阿尔托)为每名患者生成了带有 6MV 平面免滤波 (6FFF) 的容积调制弧治疗计划。Octavius 4D 系统通过将计划传送到 4D 模型来估算脊髓剂量。测量的剂量与Eclipse治疗计划系统(TPS)(瓦里安医疗系统公司,加利福尼亚州帕洛阿尔托)的剂量进行了比较:结果:使用Varisoft DVH 4D估算的脊髓最大剂量和平均剂量与TPS计算的最大剂量和平均剂量非常接近。脊髓最大剂量的测量剂量与 TPS 剂量的偏差为 ±5%,脊髓平均剂量的测量剂量与 TPS 剂量的偏差为 ±3%:该研究表明,PTW Octavius 4D 模型和 DVH 4D 功能可用作脊柱 SBRT 计划治疗前估算脊髓剂量的工具。该系统提供的独立剂量测量结果与 TPS 剂量相当。测量剂量和计算剂量之间的接近一致验证了该系统可用作关键器官剂量验证工具。
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Pretreatment Spinal Column Dose Estimation for Spinal SBRT Using Octavius Four-dimensional Phantom and Dose-volume Histograms Four-dimensional Feature: A Dosimetric Analysis.

Aim: The aim of this study was to estimate the spinal column dose for spinal Stereotactic body radiation therapy (SBRT) before patient treatment using the PTW dosimetry Octavius dose-volume histograms (DVH) four-dimensional (4D) feature.

Materials and methods: Twenty-three patients were included in the study, and a volumetric modulated arc therapy plan with 6MV flattening filter-free (6FFF) was generated for each patient in the Eclipse planning system using the Anisotropic Analytical Algorithm (AAA) algorithm (Varian Medical Systems, Palo Alto, CA) for the TrueBeam STx LINAC machine. The Octavius 4D system was used to estimate the spinal cord dose by delivering the plans to the 4D phantom. The measured dose was compared with the Eclipse treatment planning system (TPS) (Varian Medical Systems, Palo Alto, CA) dose.

Results: The spinal cord max and mean doses estimated using Varisoft DVH 4D are in close agreement with the TPS calculated max and mean doses. The deviation between measured dose and TPS dose is ±5% for the spinal max dose, and the deviation between measured dose and TPS dose is ± 3% for the spinal mean dose.

Conclusions: The study demonstrates that the PTW Octavius 4D phantom and DVH 4D feature can be used as a tool to estimate spinal cord dose before the treatment in spinal SBRT plans. The system provides an independent dose measurement that is comparable to the TPS dose. The close agreement between measured and calculated doses validates the use of this system as a critical organ dose verification tool.

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来源期刊
Journal of Medical Physics
Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.10
自引率
11.10%
发文量
55
审稿时长
30 weeks
期刊介绍: JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.
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