体力活动对慢性阻塞性肺病患者预后的影响:HADO.2 评分--健康、活动、呼吸困难和阻塞。

IF 4.3 3区 医学 Q1 RESPIRATORY SYSTEM ERJ Open Research Pub Date : 2024-01-15 eCollection Date: 2024-01-01 DOI:10.1183/23120541.00488-2023
Cristóbal Esteban, Nere Aguirre, Amaia Aramburu, Javier Moraza, Leyre Chasco, Myriam Aburto, Susana Aizpiri, Rafael Golpe, José M Quintana
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引用次数: 0

摘要

研究目的本研究旨在从多维角度制定慢性阻塞性肺病的预后工具,其中包括体力活动(PA)。该评分还包括健康状况、呼吸困难和 1 秒用力呼气量(HADO.2 评分):开展了一项前瞻性、观察性、非干预性研究。患者来自一家大学医院呼吸科的六个门诊。研究了 HADO.2 评分和 BODE 指数的组成变量,并使用加速度计测量了 PA。HADO.2 评分的结果是随访期间的死亡率和住院率,以及与纳入研究时的健康相关生活质量的相关性:研究共纳入了 401 名患者,并对其进行了为期三年的随访。HADO.2 评分对死亡率有很好的预测能力:C指数为0.79(0.72-0.85)。圣乔治呼吸问卷和慢性阻塞性肺病评估测试对住院治疗的 C 指数为 0.72(0.66-0.77),对生活质量的预测能力(以 R2 表示)分别为 0.63 和 0.53:结论:HADO.2评分和BODE指数的死亡率预测能力在统计学上没有明显差异。在原有的 BODE 指数基础上增加 PA,可显著提高该指数的预测能力。将 PA 作为关键变量的 HADO.2 评分对死亡率和住院率具有良好的预测能力。HADO.2 评分和 BODE 指数的预测能力没有差异。
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Influence of physical activity on the prognosis of COPD patients: the HADO.2 score - health, activity, dyspnoea and obstruction.

Objective: The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score).

Methods: A prospective, observational, non-intervention study was carried out. Patients were recruited from the six outpatient clinics of the respiratory service of a single university hospital. The component variables of the HADO.2 score and BODE index were studied, and PA was measured using an accelerometer. The outcomes for the HADO.2 score were mortality and hospitalisations during follow-up and an exploration of the correlation with health-related quality of life at the moment of inclusion in the study.

Results: 401 patients were included in the study and followed up for three years. The HADO.2 score showed good predictive capacity for mortality: C-index 0.79 (0.72-0.85). The C-index for hospitalisations was 0.72 (0.66-0.77) and the predictive ability for quality of life, as measured by R2, was 0.63 and 0.53 respectively for the Saint George's Respiratory Questionnaire and COPD Assessment Test.

Conclusions: There was no statistically significant difference between the mortality predictive capacity of the HADO.2 score and the BODE index. Adding PA to the original BODE index significantly improved the predictive capacity of the index. The HADO.2 score, which includes PA as a key variable, showed good predictive capacity for mortality and hospitalisations. There were no differences in the predictive capacity of the HADO.2 score and the BODE index.

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来源期刊
ERJ Open Research
ERJ Open Research Medicine-Pulmonary and Respiratory Medicine
CiteScore
6.20
自引率
4.30%
发文量
273
审稿时长
8 weeks
期刊介绍: ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.
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