乌骨鸡 Z 染色体上新型先天基因座的遗传图谱。

IF 1.6 3区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE British Poultry Science Pub Date : 2024-04-01 Epub Date: 2024-01-17 DOI:10.1080/00071668.2023.2297806
K Shiina, E Kobayashi
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引用次数: 0

摘要

1.先天性驼背 "是鸟类在孵化时表现出的一种疾病,主要症状是颈部背向后弯曲。这是一种隐性疾病,由特定基因位点的突变引起。以下研究确定了一个与乌骨鸡先天性位点相关的新位点2:正常乌骨鸡雏鸡和受先天性位点影响的乌骨鸡雏鸡在与先前罗德岛红鸡研究中报告的先天性位点相邻的 12 号染色体上的标记频率上没有差异。先天性位点受影响雏鸡的性别鉴定结果显示,这些雏鸡仅为雌性。 利用下一代测序技术进行的大量分离分析将先天性位点的致病区域缩小到 Z 染色体上 9,569,012 至 12,863,792 碱基之间约 3.3 Mb 的范围内。
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Genetic mapping of the novel congenital loco locus on chromosome Z in Silkie Fowl chickens.

1. 'Congenital loco' is a disorder in birds expressed at hatching, and the primary symptom is dorsal backward bending of the neck. It is a recessive disease caused by a mutation in a specific genetic locus. The following study identified a novel locus associated with congenital loco in Silkie Fowl chickens.2. Normal and congenital loco-affected Silkie Fowl chicks exhibited no differences in the frequencies of markers on chromosome 12 adjacent to the congenital loco locus reported in a previous study in Rhode Island Red chickens. Sex determination of congenital loco-affected chicks revealed that they were female only.3. Bulked segregant analyses using next-generation sequencing narrowed the causative region of congenital loco to approximately 3.3 Mb between bases 9,569,012 and 12,863,792 on chromosome Z.

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来源期刊
British Poultry Science
British Poultry Science 农林科学-奶制品与动物科学
CiteScore
3.90
自引率
5.00%
发文量
88
审稿时长
4.5 months
期刊介绍: From its first volume in 1960, British Poultry Science has been a leading international journal for poultry scientists and advisers to the poultry industry throughout the world. Over 60% of the independently refereed papers published originate outside the UK. Most typically they report the results of biological studies with an experimental approach which either make an original contribution to fundamental science or are of obvious application to the industry. Subjects which are covered include: anatomy, embryology, biochemistry, biophysics, physiology, reproduction and genetics, behaviour, microbiology, endocrinology, nutrition, environmental science, food science, feeding stuffs and feeding, management and housing welfare, breeding, hatching, poultry meat and egg yields and quality.Papers that adopt a modelling approach or describe the scientific background to new equipment or apparatus directly relevant to the industry are also published. The journal also features rapid publication of Short Communications. Summaries of papers presented at the Spring Meeting of the UK Branch of the WPSA are published in British Poultry Abstracts .
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