Chunmei Du, Suyu Quan, Jian Ma, Fuquan Yin, Mengsi Xu, Liuxia Lin, Guangxian Zhou, Jiang Wu, Shangquan Gan
{"title":"褐瑞士牛奶中细胞外囊泡特性和 miRNAs 图谱的表征","authors":"Chunmei Du, Suyu Quan, Jian Ma, Fuquan Yin, Mengsi Xu, Liuxia Lin, Guangxian Zhou, Jiang Wu, Shangquan Gan","doi":"10.1111/1471-0307.13049","DOIUrl":null,"url":null,"abstract":"<p>The conserved extracellular vesicles (EVs)-miRNAs from milk might potentially influence human gene expression, or even introduce their analogous nucleotide chains into the human food chain. This study aimed to characterise the features of Brown Swiss milk EVs and the EVs-miRNAs profile. Brown Swiss milk EVs exhibited a cup-shaped morphology, with a distribution of (2.3 ± 0.8) E + 11 particles/mL. Sequencing identified a total of 238 miRNAs, which were mainly implicated in immune response and cell signal transduction. The conservation of these milk EVs-miRNAs among species suggested they might be evolutionarily selected to regulate the growth and development of the newborns.</p>","PeriodicalId":13822,"journal":{"name":"International Journal of Dairy Technology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Characterisation of extracellular vesicles properties and miRNAs profiles in Brown Swiss milk\",\"authors\":\"Chunmei Du, Suyu Quan, Jian Ma, Fuquan Yin, Mengsi Xu, Liuxia Lin, Guangxian Zhou, Jiang Wu, Shangquan Gan\",\"doi\":\"10.1111/1471-0307.13049\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The conserved extracellular vesicles (EVs)-miRNAs from milk might potentially influence human gene expression, or even introduce their analogous nucleotide chains into the human food chain. This study aimed to characterise the features of Brown Swiss milk EVs and the EVs-miRNAs profile. Brown Swiss milk EVs exhibited a cup-shaped morphology, with a distribution of (2.3 ± 0.8) E + 11 particles/mL. Sequencing identified a total of 238 miRNAs, which were mainly implicated in immune response and cell signal transduction. The conservation of these milk EVs-miRNAs among species suggested they might be evolutionarily selected to regulate the growth and development of the newborns.</p>\",\"PeriodicalId\":13822,\"journal\":{\"name\":\"International Journal of Dairy Technology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-01-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Dairy Technology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/1471-0307.13049\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Dairy Technology","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/1471-0307.13049","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Characterisation of extracellular vesicles properties and miRNAs profiles in Brown Swiss milk
The conserved extracellular vesicles (EVs)-miRNAs from milk might potentially influence human gene expression, or even introduce their analogous nucleotide chains into the human food chain. This study aimed to characterise the features of Brown Swiss milk EVs and the EVs-miRNAs profile. Brown Swiss milk EVs exhibited a cup-shaped morphology, with a distribution of (2.3 ± 0.8) E + 11 particles/mL. Sequencing identified a total of 238 miRNAs, which were mainly implicated in immune response and cell signal transduction. The conservation of these milk EVs-miRNAs among species suggested they might be evolutionarily selected to regulate the growth and development of the newborns.
期刊介绍:
The International Journal of Dairy Technology ranks highly among the leading dairy journals published worldwide, and is the flagship of the Society. As indicated in its title, the journal is international in scope.
Published quarterly, International Journal of Dairy Technology contains original papers and review articles covering topics that are at the interface between fundamental dairy research and the practical technological challenges facing the modern dairy industry worldwide. Topics addressed span the full range of dairy technologies, the production of diverse dairy products across the world and the development of dairy ingredients for food applications.