在一个地理和基因隔绝的社会中,髌骨脱位和套骨发育不良的发病率很高:一项来自法罗群岛膝关节队列的全国性队列观察研究。

IF 2.5 2区 医学 Q1 ORTHOPEDICS Acta Orthopaedica Pub Date : 2024-01-18 DOI:10.2340/17453674.2024.35229
Niclas H Eysturoy, Hans-Christen Husum, Elinborg S Mortensen, Lars Blønd, Per Hölmich, Kristoffer W Barfod
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引用次数: 0

摘要

背景和目的:我们旨在计算法罗群岛 15-19 岁全国人群中髌骨脱位 (PD) 和套管发育不良 (TD) 的患病率:邀请法罗群岛所有 15-19 岁的居民回答在线调查,包括人口统计学和有关髌骨脱位的问题。曾患膝关节病的参与者受邀接受双膝X光片和核磁共振成像检查。趾骨发育不良定义为以下情况之一:X光片上的Dejour A-D型、侧蹄铁倾斜角(LTI)小于11°,或核磁共振成像上的蹄铁深度小于3毫米:共联系了 3,749 人,其中 41 人被排除在外,1,638 人(44%)完成了调查。146人报告曾患膝关节病(膝关节病队列),100人同意参与调查,并接受了双膝X光片和核磁共振成像检查(临床膝关节病队列),其中76人被诊断为膝关节病。全国PD患病率为8.9%。全国有症状的 TD 患病率为 6.8%。临床 PD 队列中的 TD 患病率为 76%。78%的TD患者为双侧TD,但只有27%的双侧TD患者双膝有PD:结论:法罗群岛的PD患病率非常高。结论:法罗群岛的膝关节退行性变发病率非常高,全国的膝关节退行性变发病率以及曾患膝关节退行性变的参与者的膝关节退行性变发病率都很高,这表明可能存在遗传影响。
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High prevalence of patellar dislocation and trochlear dysplasia in a geographically and genetically isolated society: an observational national cohort study from the Faroese Knee Cohort.

Background and purpose: We aimed to calculate the prevalence of patellar dislocation (PD) and trochlear dysplasia (TD) in a national cohort aged 15-19 years in the Faroe Island.

Patients and methods: All inhabitants in the Faroe Islands aged 15-19 years were invited to answer an online survey, including demographics and questions regarding prior PD. Participants with prior PD were invited for radiographs and MRI of both knees to be taken. Trochlear dysplasia was defined as one of the following: Dejour type A-D on radiographs, lateral trochlear inclination angle (LTI) < 11°, or trochlear depth < 3 mm on MRI.

Results: 3,749 individuals were contacted, 41 were excluded, and 1,638 (44%) completed the survey. 146 reported a prior PD (the PD cohort) and 100 accepted to participate and have radiographs and MRI taken of both knees (the clinical PD cohort), 76 of whom were diagnosed with TD. The national prevalence of PD was 8.9%. The national prevalence of symptomatic TD was 6.8%. The prevalence of TD in the clinical PD cohort was 76%. TD was bilateral in 78% of TD patients, but only 27% of patients with bilateral TD had PD in both knees.

Conclusion: The prevalence of PD in the Faroe Islands is found to be very high. The national prevalence of TD and the prevalence of TD in participants with prior PD is high, indicating a potential genetic influence.

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来源期刊
Acta Orthopaedica
Acta Orthopaedica 医学-整形外科
CiteScore
6.40
自引率
8.10%
发文量
105
审稿时长
4-8 weeks
期刊介绍: Acta Orthopaedica (previously Acta Orthopaedica Scandinavica) presents original articles of basic research interest, as well as clinical studies in the field of orthopedics and related sub disciplines. Ever since the journal was founded in 1930, by a group of Scandinavian orthopedic surgeons, the journal has been published for an international audience. Acta Orthopaedica is owned by the Nordic Orthopaedic Federation and is the official publication of this federation.
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