Anita van Eck van der Sluijs, Pearl Pai, Wenjuan Zhu, Gurbey Ocak
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引用次数: 0
摘要
心血管疾病在透析患者中发病率很高。针对这些疾病,目前正在使用抗血小板和抗血栓疗法,包括肝素、维生素 K 拮抗剂和直接口服抗凝剂。然而,与普通人群相比,透析患者使用这些疗法的收益-风险平衡可能有所不同。这篇综述文章重点探讨了血液透析患者使用肝素、抗血小板药物、维生素 K 拮抗剂和直接口服抗凝剂的相关出血风险。
Cardiovascular diseases are highly prevalent among patients on dialysis. For these diseases, antiplatelets and antithrombotic therapies including heparin, vitamin K antagonists, and direct oral anticoagulants, are being used. However, the benefit-risk balance of these therapies could differ for dialysis patients compared with the general population. This review article focuses on the bleeding risk associated with the use of heparin, antiplatelets, vitamin K antagonists, and direct oral anticoagulants in patients receiving hemodialysis.
期刊介绍:
Seminars in Nephrology is a timely source for the publication of new concepts and research findings relevant to the clinical practice of nephrology. Each issue is an organized compendium of practical information that serves as a lasting reference for nephrologists, internists and physicians in training.