伴有巩膜融解的双侧坏死性巩膜炎与单纯疱疹病毒感染有关:病例报告。

Arti Singh, Ashutosh Maharana, Srishti Nagarajan, Shubhi Sachan
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摘要

目的(Aim):本文报告了一例非常罕见的双侧单纯疱疹病毒感染并伴有双侧坏死性巩膜炎和巩膜融化的病例,患者是一名印度北部的老年女性,社会经济地位处于中下层。治疗方法一名 65 岁的女性到我院就诊,起初有神经性角膜溃疡,后来出现坏死性巩膜炎并伴有巩膜融化,病程长达 2 年。我们对患者的病历进行了评估和计算。对有关疱疹性巩膜炎的 PubMed 文献进行了检索和审查。结果:敏锐的判断力、及时的处理和对患者的指导对迅速获得良好的治疗效果至关重要。结论:伴有巩膜融解的双侧坏死性巩膜炎可能是单纯疱疹性角膜炎的一种罕见的非典型表现。在这种非典型病例中,诊断可能具有挑战性。相关的临床表现、疱疹性角膜炎病史(可能会反复发作)以及对抗病毒药物的反应可能会为这类非典型病例的诊断提供线索。此外,如果手术治疗似乎不可避免,也不应拖延。缩写:RE=右眼,LE=左眼,BCL=绷带隐形眼镜,KP=角膜沉淀,mm=毫米,mg=毫克。
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Bilateral Necrotizing Scleritis with Scleral Melt associated with Herpes Simplex Infection: A Case Report.

Objective (Aim): The article is a case report of a very rare case of bilateral herpes simplex virus infection associated with bilateral necrotizing scleritis with scleral melt in an elderly north Indian female of lower middle socioeconomic status. Methods: A 65-year-old female presented to our clinic with a wide variety of presentations ranging initially from neurotropic corneal ulcer to necrotizing scleritis with scleral melt for 2 years. The patient records were evaluated and computed. A PubMed literature search on herpes scleritis was conducted and reviewed. Results: A keen sense of judgment, timely management, and patient counseling are crucial for a rapid and favorable outcome. Conclusions: Bilateral necrotizing scleritis with scleral melt can be a rare atypical presentation of herpes simplex keratitis. In such atypical cases, diagnosis may be challenging. Associated clinical findings, history of herpes keratitis, which may be recurrent, and response to antiviral drugs, may give clues towards the diagnosis in such atypical cases. In addition to this, surgical intervention should not be delayed if it seems inevitable. Abbreviations: RE = right eye, LE = left eye, BCL = bandage contact lens, KP = keratic precipitate, mm = millimeter, mg = milligram.

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