在后腹部苍白球内植入电极治疗严重肌张力障碍性抽搐所产生的微静脉效应

IF 2.5 Q2 CLINICAL NEUROLOGY Tremor and Other Hyperkinetic Movements Pub Date : 2024-01-18 eCollection Date: 2024-01-01 DOI:10.5334/tohm.837

Galih Indra Permana, Takashi Morishita, Hideaki Tanaka, Hitoshi Iida, Shinsuke Fujioka, Hiroshi Abe

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摘要

背景：图雷特综合征（TS）是一种以运动和发音抽搐为特征的神经系统疾病。包括眼睑痉挛在内的肌张力抽搐在严重的 TS 中被认为是不典型或不寻常的：病例报告：我们报告了一例伴有类似眼睑痉挛的面部肌张力抽搐的严重 TS 病例，该病例通过双侧苍白球间质（GPi）脑深部刺激（DBS）治疗，观察到了微裂隙效应和持续的治疗效果：讨论：双侧 GPi DBS 对眼睑痉挛样抽搐和严重 TS 症状有益。讨论：双侧 GPi DBS 对眼睑痉挛样抽搐和严重 TS 症状有益，其改善可归因于在 GPi 植入 DBS 导线所产生的微缺失效应。

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Microlesion Effect Induced by Electrode Implantation in the Posteroventral Globus Pallidus Interna for Severe Dystonic Tics.

Background: Tourette syndrome (TS) is a neurologic condition characterized by motor and phonic tics. Dystonic tics, including blepharospasm, are considered atypical or unusual in severe TS.

Case report: We report a severe case of TS with facial dystonic tics resembling blepharospasm in which the microlesion effect and a sustained therapeutic effect was observed with bilateral globus pallidus interna (GPi) deep brain stimulation (DBS).

Discussion: Bilateral GPi DBS can be beneficial for blepharospasm-like tics and severe symptoms of TS. The improvements seen can be explained by the microlesion effect induced by DBS lead placement in the GPi.

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