Development of Microneedle Based Blood Extraction Device

Microneedles can extract various analytics from the human body in a minimally invasive manner and provide real-time diagnosis, making microneedle-based point-of-care testing (POCT) devices increasingly popular. In this paper, we propose a press-activated blood extraction system that integrates solid microneedles and 3D-printed blood collection devices for efficient blood extraction. The technology combines a solid microneedle array, a high-speed insertion mechanism, a negative pressure generating structure, and a blood reservoir containing lithium heparin anticoagulant into a compact, self-contained device. The device requires minimal training, as blood can be drawn with a simple finger push of the silicone chamber, yielding a blood volume of approximately 400±50 μl. This device is more convenient and less painful than finger sticks and venipuncture.