腹壁上的肿块和疙瘩:细针抽吸细胞学的作用。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.5146/tjpath.2023.12926
Anjali Ashtakar, Asha Shenoy, Mona Agnihotri, Kanchan Kothari
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引用次数: 0

摘要

目的:腹壁肿块由于症状不特异,常常给临床医生的诊断带来挑战。它们包括从炎症到肿瘤样肿块和恶性肿瘤的各种病变。大多数恶性结节源于转移,可能是原发性恶性肿瘤的最初表现;因此,早期诊断非常重要。细针穿刺细胞学(FNAC)是评估此类病变的重要诊断工具。这是一项关于腹壁肿块细胞形态学谱的回顾性研究,在一家三级医疗保健中心进行,为期三年:研究对象包括各年龄段的腹壁肿块患者。这些病变通过 FNAC 进行评估。根据细胞学涂片做出诊断,随后尽可能与组织病理学诊断相关联:在 70 例病例中,21 例为非肿瘤性,49 例为肿瘤性。良性肿瘤是最常见的病变(52.9%),其次是非肿瘤性病变(30%)和恶性肿瘤(17.1%)。脂肪瘤是最常见的良性肿瘤,转移瘤是最常见的恶性肿瘤。最常见的转移性肿瘤是腺癌,原发肿瘤主要是腹腔内肿瘤。没有发现假阴性结果:结论:大多数腹壁肿块显示出特征性的细胞形态,需要由细胞病理学家进行鉴定和识别,以做出准确诊断。FNAC 在发现转移瘤方面发挥着不可估量的作用,尤其是在脐部等部位,这可能是潜在的晚期恶性疾病的唯一表现。
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Lumps and Bumps on the Abdominal Wall: Role of Fine Needle Aspiration Cytology.

Objective: Abdominal wall masses often pose diagnostic challenges for clinicians due to their nonspecific symptoms. They include a wide spectrum of lesions ranging from inflammatory to tumor-like masses and malignancies. The majority of the malignant nodules are metastatic in origin and may be the initial presentation of a primary malignancy; hence, an early diagnosis is important. Fine-needle aspiration cytology (FNAC) is a valuable diagnostic tool in the evaluation of such lesions. This was a retrospective study of the cytomorphological spectrum of abdominal wall masses, conducted at a tertiary health care centre over a three-year period.

Material and methods: The study included patients of all age groups presenting with an abdominal wall mass. These lesions were assessed by FNAC. The diagnosis was made on cytology smears and subsequently correlated with the histopathological diagnosis, wherever possible.

Results: Of the 70 cases, 21 were non-neoplastic and 49 neoplastic. A benign neoplasm was the most common lesion (52.9%), followed by non-neoplastic lesions (30%) and malignant neoplasms (17.1%). Lipoma was the most common benign neoplasm and metastasis was the commonest malignant neoplasm. The most common type of tumor metastasising was adenocarcinoma and the primary tumors were predominantly intra-abdominal. No false-negative results were seen.

Conclusion: Most of the abdominal wall masses display a characteristic cytomorphology, which needs to be identified and recognized by a cytopathologist for an accurate diagnosis. FNAC plays an invaluable role in the detection of metastases, especially at sites such as the umbilicus, which may be the only manifestation of an underlying advanced malignant disease.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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