冠状动脉分流术后并发症的发生率;与年龄有关!

Basheer Abdullah Marzoog
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摘要

背景:目的:本研究旨在探讨衰老对冠状动脉分流术后并发症发生率的影响:衰老是每个活细胞都会经历的生理过程,从发育初期就开始了。年龄在决定术后并发症(包括与 CABG 相关的并发症)方面起着至关重要的作用:对2017年至2021年期间在莫尔多瓦共和国医院接受CABG手术的290名患者进行了回顾性分析。样本按年龄分为两组:第一组包括 126 名患者(平均年龄范围:55.21-60.00 岁),第二组包括 163 名患者(平均年龄范围:66.11-80.00 岁)。本研究采用的统计分析包括描述性统计、卡方检验、T 检验、单因素方差分析、ROC 分析和使用 Statistica 12 软件的皮尔逊相关性分析:结果:第二组的老年患者在做心导管插管术后心律失常的发生率较高(p):第二组接受心血管造影术的老年人患精神病、心律失常、长期住院和重症监护室住院以及中风的风险更高。心律失常常见于 63 岁及以上的患者,会显著影响总住院天数。并发症的数量受年龄、心肺旁路(CPB)时间、主动脉交叉钳夹时间、重症监护室住院时间和总住院时间的影响。
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Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!

Background: Numerous complications, such as postoperative arrhythmia and stroke, have been observed following coronary artery bypass graft (CABG) surgery.

Aims: This study sought to examine the impact of aging on the incidence of post-coronary artery shunt complications.

Objectives: Aging is a physiological process experienced by every living cell, beginning early in development. Age plays a crucial role in determining postoperative complications, including those related to CABG.

Materials and methods: A retrospective analysis was conducted on 290 patients who underwent CABG at the Mordovian Republic Hospital between 2017 and 2021. The sample was divided into two age-based groups: the first group comprised 126 patients (mean age range: 55.21-60.00), and the second group included 163 patients (mean age range: 66.11-80.00). Statistical analyses employed in this study encompassed descriptive statistics, Chi-square test, T-test, one-way ANOVA test, ROC analysis, and Pearson correlation using Statistica 12 software.

Results: Elderly patients in the second group demonstrated a higher incidence of post-CABG arrhythmia (p < 0.012528). Moreover, the second group experienced markedly longer ICU and total hospitalization days following CABG, with p-values of less than 0.000000 and 0.000072, respectively. Notably, elderly individuals in the second group faced an increased risk of developing psychosis after CABG surgery (p < 0.007379). Furthermore, psychosis was found to be significantly associated with longer ICU hospitalization (p < 0.000140). Postoperative stroke occurred more frequently among the elderly (second group) with a p-value of less than 0.037736. Consequently, postoperative stroke was associated with extended ICU hospitalization (p < 0.000747). The usage of internal thoracic arteries (ITAs) was lower among the elderly (second group), with a p-value of less than 0.016145. Regarding correlations, a direct association was observed between age and ICU days, total hospitalization days, and the number of complications, with correlation coefficients (r) of 0.189046, 0.141415, and 0.138565, respectively.

Conclusion: Elderly individuals in the second group who undergo CABG face a greater risk of developing psychosis, arrhythmia, prolonged total and ICU hospitalization, and stroke. The presence of arrhythmia, which is commonly observed in patients aged 63 years and older, significantly affects total hospitalization days. The number of complications is influenced by age, cardiopulmonary bypass (CPB) time, aortic cross-clamp time, ICU hospitalization, and total hospitalization duration.

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