经巩膜环形消融术后内窥镜激光环形凝固术与再次经巩膜治疗的成功对比

Christiane Al-Haddad, Anita Barikian, Zeinab El Moussawi, Nour A Nasser, Bahaa' Noureddine, Ziad Bashshur
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引用次数: 0

摘要

目的:比较内窥镜环形光凝术(ECP)与重复经巩膜环形光凝术(TCP)对曾接受过 TCP 治疗但青光眼持续存在的眼睛的疗效:这是对贝鲁特美国大学医疗中心 10 年来接受 ECP 或重复 TCP 治疗的青光眼患者进行的回顾性病历审查。我们报告了合格和完全成功的情况;成功的定义是术后眼压(IOP)≤21 mm Hg,用药(合格)或不用药(完全)且无手术相关并发症:本研究共纳入了 21 名各种形式的未控制青光眼患者的 23 只眼睛,他们都曾接受过失败的 TCP 治疗。其中,12 名患者的 13 只眼睛接受了 ECP,平均年龄为(39.9 ± 23.2)岁;9 名患者的 10 只眼睛接受了重复 TCP,平均年龄为(27.2 ± 22.6)岁。平均随访时间分别为 39.2 ± 44.4 个月和 41.5 ± 37.4 个月时,观察到眼压明显下降,从术前的 38.5 ± 7.9 mm Hg 降至重复 TCP 术后的 25.2 ± 8.8 mm Hg(p = 0.006),从 ECP 术后的 33.0 ± 9.5 mm Hg 降至 12.8 ± 3.9 mm Hg(p < 0.001)。两组患者的平均抗青光眼药物用量均有所下降(ECP 从术前的 3.8 ± 1.0 降至术后的 1.8 ± 0.9,TCP 从术前的 3.5 ± 1.3 降至术后的 3.1 ± 0.9);但只有在 ECP 术后,降幅才有统计学意义。ECP 与重复 TCP 相比,合格成功率明显更高(分别为 91.7% 与 40%)。结论:结论:与重复 TCP 相比,对曾接受过经巩膜环形消融术治疗的青光眼眼球进行内窥镜环形光凝术(ECP),通过直接治疗先前跳过的睫状突和睫状突间的有活力组织,能更好地控制眼压:在曾接受过经巩膜环形消融术治疗的青光眼患者中,ECP比重复经巩膜环形消融术能更好地控制眼压:Al-Haddad C, Barikian A, Moussawi ZE, et al. 内镜激光环形消融术与重复经巩膜环形消融术治疗的成功对比。J Curr Glaucoma Pract 2023;17(4):191-196.
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Success of Endoscopic Laser Cyclophotocoagulation vs Repeat Transscleral Treatment after Prior Transscleral Cycloablation.

Aim: To compare the efficacy of endoscopic cyclophotocoagulation (ECP) vs repeat transscleral cyclophotocoagulation (TCP) in eyes with persistent glaucoma despite prior treatment with TCP.

Materials and methods: This was a retrospective chart review of glaucoma patients at the American University of Beirut Medical Center over 10 years who underwent ECP or repeat TCP. We reported qualified and complete success; success was defined as postoperative intraocular pressure (IOP) ≤21 mm Hg, with (qualified) or without medications (complete) and without procedure-related complications.

Results: This study included 23 eyes of 21 patients with various forms of uncontrolled glaucoma who had failed TCP. A total of 13 eyes of 12 patients underwent ECP with a mean age of 39.9 ± 23.2 years, and 10 eyes of nine patients underwent repeat TCP with a mean age of 27.2 ± 22.6 years. A significant decrease in IOP was observed from 38.5 ± 7.9 mm Hg preoperatively to 25.2 ± 8.8 mm Hg postrepeat TCP (p = 0.006) and from 33.0 ± 9.5 to 12.8 ± 3.9 mm Hg post-ECP (p < 0.001), noted at a mean follow-up time of 39.2 ± 44.4 and 41.5 ± 37.4 months, respectively. The mean number of antiglaucoma medications decreased in the two groups (from 3.8 ± 1.0 preoperatively to 1.8 ± 0.9 postoperatively for ECP and from 3.5 ± 1.3 to 3.1 ± 0.9 postoperatively for TCP); however, the drop was only statistically significant post-ECP. Qualified success was significantly higher after ECP vs repeat TCP (91.7 vs 40%, respectively). Complete success was achieved only in 1/12 (8.3%) eyes in the ECP group.

Conclusion: Endoscopic cyclophotocoagulation (ECP) performed in glaucomatous eyes previously treated with transscleral cycloablation provided more IOP control as compared to repeat TCP by directly treating viable tissue in previously skipped ciliary processes and in between processes.

Clinical significance: In glaucomatous eyes previously treated with transscleral cycloablation, ECP attained better IOP control than repeat transscleral cycloablation.

How to cite this article: Al-Haddad C, Barikian A, Moussawi ZE, et al. Success of Endoscopic Laser Cyclophotocoagulation vs Repeat Transscleral Treatment after Prior Transscleral Cycloablation. J Curr Glaucoma Pract 2023;17(4):191-196.

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Journal of Current Glaucoma Practice
Journal of Current Glaucoma Practice Medicine-Ophthalmology
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