[老年人心肌梗死的急性期]。

Zeitschrift fur Alternsforschung Pub Date : 1989-09-01
K Kothe, R Aurisch, B Porstmann
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引用次数: 0

摘要

老年AMI患者占总患者的比例占主导地位,并仍在不断增加。最根本的原因是28天前并发症和死亡率的增加。在一项为期48个月的前瞻性研究中,我们分析了年龄小于65岁(a)和大于或等于65岁(B)的患者的不同并发症发生率。对于心肌梗死大小的半定量测定,我们使用:-监测ECG,肌酸酐激酶(CK)和射血分数(EFg)。A组81%存活,而B组只有60%存活。存活患者平均年龄56.2岁,死亡患者平均年龄64.4岁。在A、b两组中,CKmax在非跨壁AMI和跨壁AMI之间存在显著差异,p < 0.01。死者CKmax为89.7 (A) ~ 59.3 mumol/lxs (B) (p < 0.05)。A组AMI扩展率为4%,B组为43%,p < 0.005。B组非经壁AMI的心电图差异有统计学意义(p < 0.001),分别为59.1%(36-70)%、31.5%和17.3%。Re-AMI患者的脑电图通常小于45%。Re-AMI在A组患者中的诊断率为13%,在B组患者中为29% (p < 0.001)。1984年至1987年期间,总患者中幸存患者的ICU住院时间可减少1.1天。B组可缩短0.8天。总住院时间(1984-1987)为19.6天(A = 18.3;B = 22.4)。AMI的延长和再AMI的结果是老年AMI并发症和死亡病例增加的决定性因素。通过监测半定量确定心肌梗死大小,为早期评估心肌残余功能和危险性分级提供了有效依据。
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[The acute phase of myocardial infarct in the elderly].

The percentage of older patients with AMI in the total of patients is predominating and is still increasing differentiatedly. The essential cause of there is an increase in complications and in mortality until the 28th day. In a prospective study over 48 months with n = 390 patients we analyzed the age groups less than 65 years (A) and greater than or equal to 65 years (B) regarding their different rates of complications. For the semiquantitative determination of myocardial infarction sizes we used: -Monitoring of ECG, creatinine kinase (CK), and ejection fraction global (EFg). In group A 81% survived, whereas in group B only 60% survived. The average age of the surviving patients was 56.2 years, that of the deceased 64.4 years. The percentage of surviving patients with transmural AMI was 96% in A and 57% in B. In both A and B. CKmax with p less than 0.01 was to be differentiated between non-transmural and transmural AMI. In the deceased CKmax was 89.7 (A) to 59.3 mumol/lxs (B) (p less than 0.05). The percentage with AMI extension was 4% in A and 43% in B, p less than 0.005. Patients of group B showed a significant difference (p less than 0.001) of EFg for non-transmural AMI 59.1 (36-70)%, transmural AMI 31.5%, and deceased 17.3%. In patients with Re-AMI EFg was generally measured to be less than 45%. Re-AMI could be diagnosed in 13% of A and in 29% of B (p less than 0.001). The ICU stay of the surviving patients of the total number of patients could be reduced by 1.1 days in the period from 1984 through 1987. With group B it could be reduced by 0.8 days. The overall stay in hospital (1984-1987) was 19.6 days (A = 18.3; B = 22.4). AMI extension and the Re-AMI result are the decivise factors to the essential increase in complications and cases of death with AMI at older age. The semiquantitative determination of the myocardial infarction size by monitoring makes up an efficient basis for the early assessment of the residual function of the myocardium and of the risk classification.

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