{"title":"神经性疼痛影响化疗引起周围神经病变的乳腺癌幸存者的生活质量","authors":"You-Wun Jheng R.N., M.S.N. , Ya-Ning Chan R.N., Ph.D. , Chih-Jung Wu R.N., Ph.D. , Ming-Wei Lin Ph.D. , Ling-Ming Tseng M.D. , Ya-Jung Wang R.N., Ph.D.","doi":"10.1016/j.pmn.2023.12.013","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter.</p></div><div><h3>Aims</h3><p>This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy.</p></div><div><h3>Design</h3><p>A cross-sectional, correlational design.</p></div><div><h3>Settings</h3><p>This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan.</p></div><div><h3>Participants/Subjects</h3><p>One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled.</p></div><div><h3>Methods</h3><p>Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast.</p></div><div><h3>Results</h3><p>The study indicated that improving depression (B = –10.87, <em>p</em> < .001) and neuropathic pain (B = –8.33, <em>p</em><span> = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors.</span></p></div><div><h3>Conclusions</h3><p>This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.</p></div>","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neuropathic Pain Affects Quality of Life in Breast Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy\",\"authors\":\"You-Wun Jheng R.N., M.S.N. , Ya-Ning Chan R.N., Ph.D. , Chih-Jung Wu R.N., Ph.D. , Ming-Wei Lin Ph.D. , Ling-Ming Tseng M.D. , Ya-Jung Wang R.N., Ph.D.\",\"doi\":\"10.1016/j.pmn.2023.12.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter.</p></div><div><h3>Aims</h3><p>This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy.</p></div><div><h3>Design</h3><p>A cross-sectional, correlational design.</p></div><div><h3>Settings</h3><p>This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan.</p></div><div><h3>Participants/Subjects</h3><p>One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled.</p></div><div><h3>Methods</h3><p>Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast.</p></div><div><h3>Results</h3><p>The study indicated that improving depression (B = –10.87, <em>p</em> < .001) and neuropathic pain (B = –8.33, <em>p</em><span> = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors.</span></p></div><div><h3>Conclusions</h3><p>This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.</p></div>\",\"PeriodicalId\":19959,\"journal\":{\"name\":\"Pain Management Nursing\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pain Management Nursing\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1524904223002503\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NURSING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pain Management Nursing","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1524904223002503","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NURSING","Score":null,"Total":0}
Neuropathic Pain Affects Quality of Life in Breast Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy
Background
Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter.
Aims
This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy.
Design
A cross-sectional, correlational design.
Settings
This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan.
Participants/Subjects
One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled.
Methods
Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast.
Results
The study indicated that improving depression (B = –10.87, p < .001) and neuropathic pain (B = –8.33, p = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors.
Conclusions
This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.
期刊介绍:
This peer-reviewed journal offers a unique focus on the realm of pain management as it applies to nursing. Original and review articles from experts in the field offer key insights in the areas of clinical practice, advocacy, education, administration, and research. Additional features include practice guidelines and pharmacology updates.