GeneConnector:释放基因库元数据的全部潜力

IF 1.3 4区 工程技术 Q3 COMPUTER SCIENCE, INFORMATION SYSTEMS IEEE Latin America Transactions Pub Date : 2024-01-23 DOI:10.1109/TLA.2024.10412034
Samuel Galvao Elias;Debora Cervieri Guterres;Robert Weingart Barreto;Helson Mario Martins do Vale
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引用次数: 0

摘要

基因库目前是全球最重要的基因信息库之一。然而,尽管数据数量庞大、种类繁多,现有记录中仍有相当一部分存在元数据不连贯且经常缺失的问题,无法提供获取数据的必要背景。有鉴于此,我们提出了基因连接器(GeneConnector)这一工具,它能利用 Genbank 中同一标本的多条记录之间的共享信息,旨在提高不同信息领域中注释不全的节点的完整性。为了展示该工具的能力,我们利用 Genbank 植物病原真菌属(GOPHY)数据库对现有数据进行了全面审查和汇总。通过评估,我们观察到,通过分析连接 Genbank 标本记录的节点之间的共享数据,信息量大幅增加,增幅从 2% 到 60% 不等,令人印象深刻。我们的方法使用户能够对与结果相关的上下文进行精确、直接和准确的评估,并通过两个指标来衡量当前的数据注释水平和我们评估后可实现的潜在信息增益。
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GeneConnector: Unlocking the full potential of Genbank metadata
Genbank currently stands as one of the most significant global repositories of genetic information. However, despite its vast quantity and diversity of data, a considerable portion of the existing records suffer from disjointed and often lacking metadata, failing to provide the necessary context of their acquisition. In light of this, we propose GeneConnector, a tool that harnesses shared information among multiple records of the same specimen in Genbank, aiming to enhance the completeness of poorly annotated nodes across various information domains. To demonstrate the tools capabilities, we conducted a comprehensive review and aggregation of available data using the Genbank database of Genera of Phytopathogenic Fungi (GOPHY). Through our evaluation, we observed substantial gains in information by analyzing shared data among nodes connecting Genbank specimen records, resulting in impressive increments ranging from 2% to a remarkable 60%. Our approach empowers users to make precise, straightforward, and accurate assessments of the context associated to results, facilitated by two metrics that gauge the current level of data annotation and the potential information gain achievable following our evaluation.
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来源期刊
IEEE Latin America Transactions
IEEE Latin America Transactions COMPUTER SCIENCE, INFORMATION SYSTEMS-ENGINEERING, ELECTRICAL & ELECTRONIC
CiteScore
3.50
自引率
7.70%
发文量
192
审稿时长
3-8 weeks
期刊介绍: IEEE Latin America Transactions (IEEE LATAM) is an interdisciplinary journal focused on the dissemination of original and quality research papers / review articles in Spanish and Portuguese of emerging topics in three main areas: Computing, Electric Energy and Electronics. Some of the sub-areas of the journal are, but not limited to: Automatic control, communications, instrumentation, artificial intelligence, power and industrial electronics, fault diagnosis and detection, transportation electrification, internet of things, electrical machines, circuits and systems, biomedicine and biomedical / haptic applications, secure communications, robotics, sensors and actuators, computer networks, smart grids, among others.
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