Scott M. Matson, Linh T. Ngo, Yui Sugawara, Veani Fernando, Claudia Lugo, Imaan Azeem, Alexis Harrison, Alex Alsup, Emily Nissen, Devin Koestler, Michael P. Washburn, Michaella J. Rekowski, Paul J. Wolters, Joyce S. Lee, Joshua J. Solomon, M. Kristen Demoruelle
{"title":"中性粒细胞胞外捕获物的形成与特发性肺纤维化的严重程度和存活率有关","authors":"Scott M. Matson, Linh T. Ngo, Yui Sugawara, Veani Fernando, Claudia Lugo, Imaan Azeem, Alexis Harrison, Alex Alsup, Emily Nissen, Devin Koestler, Michael P. Washburn, Michaella J. Rekowski, Paul J. Wolters, Joyce S. Lee, Joshua J. Solomon, M. Kristen Demoruelle","doi":"10.1101/2024.01.24.24301742","DOIUrl":null,"url":null,"abstract":"<strong>Rationale</strong> Neutrophil counts in bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis are associated with worse outcomes; however, the underlying mechanisms are unknown. Neutrophil extracellular trap formation is associated with worse outcomes in several chronic lung diseases however, there is an unknown role in idiopathic pulmonary fibrosis.","PeriodicalId":501074,"journal":{"name":"medRxiv - Respiratory Medicine","volume":"51 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neutrophil extracellular trap formation linked to idiopathic pulmonary fibrosis severity and survival\",\"authors\":\"Scott M. Matson, Linh T. Ngo, Yui Sugawara, Veani Fernando, Claudia Lugo, Imaan Azeem, Alexis Harrison, Alex Alsup, Emily Nissen, Devin Koestler, Michael P. Washburn, Michaella J. Rekowski, Paul J. Wolters, Joyce S. Lee, Joshua J. Solomon, M. Kristen Demoruelle\",\"doi\":\"10.1101/2024.01.24.24301742\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Rationale</strong> Neutrophil counts in bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis are associated with worse outcomes; however, the underlying mechanisms are unknown. Neutrophil extracellular trap formation is associated with worse outcomes in several chronic lung diseases however, there is an unknown role in idiopathic pulmonary fibrosis.\",\"PeriodicalId\":501074,\"journal\":{\"name\":\"medRxiv - Respiratory Medicine\",\"volume\":\"51 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Respiratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.24.24301742\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Respiratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.24.24301742","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neutrophil extracellular trap formation linked to idiopathic pulmonary fibrosis severity and survival
Rationale Neutrophil counts in bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis are associated with worse outcomes; however, the underlying mechanisms are unknown. Neutrophil extracellular trap formation is associated with worse outcomes in several chronic lung diseases however, there is an unknown role in idiopathic pulmonary fibrosis.
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