低强度激光疗法和低强度脉冲超声波对实验性周围神经损伤 Wistar 大鼠运动恢复的影响

Illavenil J, Prathap Suganthirababu, Lavanya Prathap, Mydhili Govindarasu, Kumaresan. A, Vignesh Srinivasan, Jagatheesan alagesan
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摘要

背景:损伤或疾病可导致周围神经损伤,这是一个常见的临床问题。它经常导致严重的感觉缺失和运动障碍,并伴有疼痛、刺痛、灼热和其他令人烦恼的感觉,从而使人致残。一种名为低强度脉冲超声波的超声波,其能量远低于普通超声波(3 瓦/平方厘米)。目的:本研究旨在找出低强度激光疗法和低强度脉冲超声波对实验性周围神经损伤 Wistar 大鼠运动恢复的影响:选取18只大鼠,拔除皮毛暴露坐骨神经区域,用止血钳压迫损伤30秒,1组为超声组,2组为激光组,3组为对照组。采用步长比(SLR)作为评估运动恢复的结果指标:结果:在干预期间(第 7 天、第 24 天、第 21 天),使用单因素方差分析,三组均有统计学意义(P<0.001),但 LLLT 和 UST 在功能指数方面的改善优于对照组:根据研究结果,LLLT 比 LIPU 对运动恢复的影响更大,而且每种治疗方法对加速神经再生和缩短恢复时间都有实质性影响。
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Effectiveness of low-level Laser Therapy and Low Intensity Pulsed Ultrasound on Motor Recovery among Experimentally Induced Peripheral Nerve Injury in Wistar Rats
Background: Damage or disease can result in peripheral nerve injury, which is a frequent clinical issue. It frequentlyrenders a person disabled by causing severe sensory loss and motor deficiencies along with pain, tingling, burningand other nagging sensations. A form of ultrasound called Low-intensity pulsed ultrasound, which uses far lessenergy than normal ultrasound (3 W/cm2). A biological reaction is triggered by low-level laser light having awavelength of 808nm and a power range of 1-1000 mW.Purpose: The Study is to find out the effect of low-level laser therapy and low intensity pulsed ultrasound onmotor recovery among experimentally induced peripheral nerve injury in Wistar rats.Methods: Eighteen rats were chosen in total, skin hair was removed to expose the sciatic nerve area, and the crushinjury was done by hemostatic forceps for 30 seconds, the group 1 is ultrasound, group 2 is laser and group 3 iscontrol group. The Step Length Ratio (SLR) was used as an outcome measure to assess motor recovery.Result: All three groups are statistically significant (p<0.001) was analysed using one-way ANOVA duringintervention period (7th, 24th, 21st day) but LLLT & UST has shown better improvement in their functional indexthan the control group.Conclusion: According to the results, LLLT has more impact in motor recovery than LIPU also each treatment hassubstantial impact on accelerating nerve regeneration and shortening the recovery time.
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