The effectiveness of vaccination in acute postpartum endometritis of cows

The article presents the results of studies of the vaccine against infectious mastitis and acute postpartum endometritis of cows inactivated. The specific efficacy of the vaccine was determined by the number of cases of cows with endometritis. The disease was recorded in 14.2% of the experimental and 52.5% of the animals in the control group within a month after calving.An experiment was conducted comparing the effectiveness of two immunization regimens, the first of which provides for primary vaccination of pregnant animals, the second — the beginning of immunization of heifers from 6–8 months of age, followed by a single injection every 6 months at a dose of 3 ml. During the experiment, endometritis was detected in 10% of cows in the 1st and 2nd experimental groups, which is 3.7 times lower than in animals in the control group (36.6%). Thus, it was established that both animal immunization schemes are effective in combating the incidence of calving cows with endometritis.When studying the intrauterine secretions of cows with endometritis, a significant effect of immunization on the species composition of pathogens was established. Thus, in cows of the control group, E.coli with endometritis was isolated 3.4 times more often than in animals of the experimental group. A similar pattern was observed for other microorganisms: the number of S. aureus isolates detected was 2.2 times less in the experimental group, S. agalactiae — 15.0 times, S. dysgalactiae — 2.0 times, S. uberis — 6.0 times, S. pyogenes — 3.0 times, K. pneumoniae — 3.4 times less in comparison with the control group.