继发性帕金森综合症对健康状况的影响

Dawid Kościołek, Michał Urbaś, Jakub Misiak, Aleksandra Kościołek, Martyna Kępczyk, Oliwia Czekaj, Miłosz Ojdana, Kaja Surowiecka, Oliwia Kwaśniewska, Yehor Demianenko
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摘要

导言和工作目的:帕金森综合征是帕金森病的一个组成部分。全面的神经系统检查可以发现属于帕金森综合征的症状。根据皇后广场脑库的诊断标准,患者在出现运动迟缓的同时,还需伴有其他症状。这些症状包括肌肉僵直或频率为 4-6 赫兹的静止性震颤,或无法用视觉、前庭、小脑或深感觉障碍来解释的姿势障碍。帕金森综合征可发生于特发性帕金森病、遗传性疾病、继发性帕金森病,也可作为非典型帕金森综合征的一部分。本研究旨在讨论帕金森综合征作为帕金森病的一个组成部分,在其他神经系统疾病中的诊断特征和发生差异:研究的基础是从谷歌学术数据库中收集的医学论文。研究通过分析 "帕金森病"、"药物性帕金森病 "和 "血管性帕金森病 "等关键词进行:继发性帕金森病或继发性帕金森综合征的临床特征包括:发病年龄低于40岁、突然发病、疾病进展迅速、与用药相关的症状以及与潜在疾病相关的症状。除临床评估外,还可采用影像学检查。继发性帕金森病的发病原因多种多样,包括脑积水、脑肿瘤、脑炎、脑动脉粥样硬化、脑外伤、药物和中毒等。上述病症对中枢神经系统的影响机制各不相同。
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The effects that secondary parkinsonian syndromes have on health status
Introduction and aim of work: The parkinsonian syndrome is a component of Parkinson's disease. A thorough neurological examination can detect symptoms belonging to the parkinsonian syndrome. Diagnosis using the Queen Square Brain Bank criteria is based on the presence of bradykinesia along with one additional symptom in the patient. These include muscle rigidity or resting tremors at a frequency of 4-6 Hz, or postural disturbances that cannot be explained by visual, vestibular, cerebellar, or deep sensory disorders. The parkinsonian syndrome can occur in idiopathic Parkinson's disease, hereditary disorders, secondary parkinsonism, or be part of an atypical parkinsonian syndrome. The aim of the study was to discuss the diagnostic features and differences in the occurrence of the parkinsonian syndrome as a component of Parkinson's disease, both within the context of other neurological disorders. Materials and methods: The foundation of the research was medical articles gathered from the Google Scholar database. The studies were conducted by analyzing keywords such as "parkinsonism," "drug-induced parkinsonism," and "vascular parkinsonism." Results: Secondary parkinsonism, or secondary parkinsonism syndrome, can be indicated by clinical features such as: disease onset below the age of 40, abrupt onset, rapid disease progression, symptoms related to medication use, and symptoms associated with the underlying condition. In addition to clinical evaluation, imaging studies are also employed. Various conditions can lead to the development of secondary parkinsonism, including hydrocephalus, brain tumors, encephalitis, cerebral atherosclerosis, traumatic brain injuries, medications, and poisoning. The aforementioned conditions exert different mechanisms of influence on the central nervous system.
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