接受减肥手术的 II 型糖尿病患者术前 24 小时暂停服用 SGLT2 抑制剂对缓解优格症糖尿病酮症酸中毒的疗效。

IF 1 Q4 ENDOCRINOLOGY & METABOLISM Diabetes epidemiology and management Pub Date : 2024-01-24 DOI:10.1016/j.deman.2024.100201
Samer Younes
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引用次数: 0

摘要

该病例强调了减肥手术和使用 SGLT2 抑制剂后发生优生糖尿病酮症酸中毒 (DKA) 的风险,突出了患者教育和医疗服务提供者监控的重要性。潜在的原因包括 SGLT2 抑制剂导致尿糖排泄增加、术后碳水化合物摄入减少以及可能的胰岛素停药效应。目前 AACE 建议在手术前 24 小时停用 SGLT2 抑制剂,这可能需要更多的研究来确定最佳停药时间。
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The efficacy of a 24-hour preoperative pause for SGLT2-inhibitors in type II diabetes patients undergoing bariatric surgery to mitigate euglycemic diabetic ketoacidosis

The case emphasizes the risk of euglycemic diabetic ketoacidosis (DKA) after bariatric surgery and SGLT2 inhibitor use, highlighting the importance of patient education and healthcare provider monitoring. Potential causes include increased urinary glucose excretion from SGLT2 inhibitors, reduced carbohydrate intake post-surgery, and possible insulin discontinuation effects. The current recommendation from AACE to discontinue SGLT2 inhibitors 24 h before surgery may require additional research to determine the optimal timing of discontinuation.

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来源期刊
Diabetes epidemiology and management
Diabetes epidemiology and management Endocrinology, Diabetes and Metabolism, Public Health and Health Policy
CiteScore
1.10
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审稿时长
14 days
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