萎缩性肾脏样病变--病例报告和文献综述

IF 0.9 4区医学 Q4 PATHOLOGY International Journal of Surgical Pathology Pub Date : 2024-10-01 Epub Date: 2024-01-30 DOI:10.1177/10668969241226703

Xin Wang, Elizabeth Lovelace, Richard R Pacheco, Robert Pacheco, Michael E Schuster, Adrien Bernstein, Mahmut Akgul, Andrea Lightle

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引用次数: 0

摘要

萎缩性肾脏样病变（AKLL）是一种罕见的肾脏病变，最近被泌尿生殖系统病理学会建议为一个临时实体。截至目前，文献中已描述了 16 例 AKLL。在此，我们报告了一种新的肿瘤，其临床病理特征与之前报告的 AKLL 相似。免疫组化（IHC）研究发现，该病变具有双相染色模式，由WT1+/KRT7-/PAX8-大扩张囊肿和WT-/KRT7+/PAX8+小萎缩囊肿混合组成。AKLL的组织形态学特征与多种肿瘤和非肿瘤实体重叠，可能导致定性错误。在评估这些病变时，对鉴别特征的认识可能非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Atrophic Kidney-Like Lesion-Case Report and Review of the Literature.

Atrophic kidney-like lesion (AKLL) is a rare kidney lesion, which was recently suggested by the Genitourinary Pathology Society as a provisional entity. As of now, 16 examples of AKLL have been described in the literature. Here we report a new tumor which shows similar clinicopathologic characteristics with those previously reported in AKLL. Immunohistochemical (IHC) studies in the current lesion identified a biphasic staining pattern consisting of a mixture of WT1+/KRT7-/PAX8- large dilated cysts and WT-/KRT7+/PAX8+ small atrophic cysts. Histomorphologic features of AKLL overlap with several neoplastic and non-neoplastic entities which can lead to mischaracterization. Awareness of the differentiating features is likely important when evaluating these lesions.

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来源期刊

International Journal of Surgical Pathology 医学-病理学

CiteScore

2.10

自引率

0.00%

发文量

198

审稿时长

1 months

期刊介绍： International Journal of Surgical Pathology (IJSP) is a peer-reviewed journal published eight times a year, which offers original research and observations covering all major organ systems, timely reviews of new techniques and procedures, discussions of controversies in surgical pathology, case reports, and images in pathology. This journal is a member of the Committee on Publication Ethics (COPE).