{"title":"为免疫相关炎症性疾病接种 SARS-CoV-2 疫苗提供更多令人欣慰的数据，但也有陷阱。","authors":"Alfred H J Kim","doi":"10.3899/jrheum.2024-0006","DOIUrl":null,"url":null,"abstract":"Vaccination remains the most important intervention to attenuate the risk and severity of infectious diseases in those immunosuppressed for the treatment of rheumatic conditions and is indeed true for coronavirus disease 2019 (COVID-19). Substantial reductions in the hazard ratios (HRs) of breakthrough infections were observed in those with immune-mediated inflammatory diseases (IMIDs) vaccinated with the initial series (HR 0.143) and after the third dose (HR 0.017) of BNT162b2 compared to unvaccinated patients.<sup>1</sup>.","PeriodicalId":501812,"journal":{"name":"The Journal of Rheumatology","volume":"164 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Additional Reassuring Data for SARS-CoV-2 Vaccination in Immune-Mediated Inflammatory Diseases, but With a Catch.\",\"authors\":\"Alfred H J Kim\",\"doi\":\"10.3899/jrheum.2024-0006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Vaccination remains the most important intervention to attenuate the risk and severity of infectious diseases in those immunosuppressed for the treatment of rheumatic conditions and is indeed true for coronavirus disease 2019 (COVID-19). Substantial reductions in the hazard ratios (HRs) of breakthrough infections were observed in those with immune-mediated inflammatory diseases (IMIDs) vaccinated with the initial series (HR 0.143) and after the third dose (HR 0.017) of BNT162b2 compared to unvaccinated patients.<sup>1</sup>.\",\"PeriodicalId\":501812,\"journal\":{\"name\":\"The Journal of Rheumatology\",\"volume\":\"164 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Rheumatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3899/jrheum.2024-0006\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Rheumatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3899/jrheum.2024-0006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Additional Reassuring Data for SARS-CoV-2 Vaccination in Immune-Mediated Inflammatory Diseases, but With a Catch.
Vaccination remains the most important intervention to attenuate the risk and severity of infectious diseases in those immunosuppressed for the treatment of rheumatic conditions and is indeed true for coronavirus disease 2019 (COVID-19). Substantial reductions in the hazard ratios (HRs) of breakthrough infections were observed in those with immune-mediated inflammatory diseases (IMIDs) vaccinated with the initial series (HR 0.143) and after the third dose (HR 0.017) of BNT162b2 compared to unvaccinated patients.1.
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