免疫功能正常患者腿部皮肤溃疡感染 Kodamaea ohmeri：病例报告。

IF 2 4区医学 Q3 ONCOLOGY Chemotherapy Pub Date : 2024-01-01 Epub Date: 2024-02-01 DOI:10.1159/000536588

Angelo Aita, Diana Lelli, Giovanni Gherardi, Claudio Pedone, Raffaele Antonelli Incalzi

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引用次数: 0

摘要

简介：Kodamaea ohmeri（K：Kodamaea ohmeri（K. ohmeri）是一种新出现的真菌，被认为是免疫功能低下宿主的重要病原体，可导致危及生命的感染：我们描述了一例 69 岁免疫功能健全的男性腿部皮肤溃疡病史。这是首例免疫功能正常的患者腿部伤口感染欧鼠李的病例。感染后，每天使用 200 毫克伏立康唑进行治疗，取得了成功：结论：尽管K. ohmeri很罕见，但对于那些对药物治疗反应不佳的皮肤溃疡患者，即使没有免疫力低下，也应考虑感染K. ohmeri。

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Kodamaea ohmeri Leg Skin Ulcer Infection in an Immunocompetent Patient: A Case Report.

Introduction: Kodamaea ohmeri is an emerging fungus recognised as an important pathogen in immunocompromised hosts, responsible for life-threatening infections.

Case presentation: We describe a case of a 69-year-old immunocompetent man with a long history of leg skin ulcers infected by K. ohmeri. This is the first case of leg wounds infected by K. ohmeri in an immunocompetent patient. The infection was successfully treated with voriconazole 200 mg daily.

Conclusion: Though rare, K. ohmeri should be considered in patients with skin ulcers that are poorly responsive to medical treatment, even if not immunocompromised.

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来源期刊

Chemotherapy 医学-药学

CiteScore

5.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal publishes original research articles and state-of-the-art reviews on all aspects of antimicrobial and antitumor chemotherapy. The results of experimental and clinical investigations into the microbiological and pharmacologic properties of antibacterial, antiviral and antitumor compounds are major topics of publication. Papers selected for the journal offer data concerning the efficacy, toxicology, and interactions of new drugs in single or combined applications. Studies designed to determine the pharmacokinetic and pharmacodynamics properties of similar preparations and comparing their efficacy are also included. Special emphasis is given to the development of drug-resistance, an increasing problem worldwide.