Phytobase 和 HRT 重奶油碱中各种激素的兼容性。

Q4 Medicine International journal of pharmaceutical compounding Pub Date : 2024-01-01
Sarah Taylor, Rodney Haselhorst
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引用次数: 0

摘要

美国药典》章节的发布和《美国药典》章节的修订(2023 年 11 月 1 日正式发布)表明,监管环境正在发生变化,对超出指南建议的默认使用日期的延长标准也有越来越高的趋势。鉴于审查的加强和对延长使用期限的额外要求,需要进行更多的测试来帮助药房提供具有科学可靠数据的最佳配方,以支持延长使用期限,方便患者。本研究的目的是通过评估两种载体(Phytobase 和 HRT Heavy)在使用常见激素组合时的稳定性和抗菌效果,证明这两种载体适用于复方激素疗法。
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Compatibility of Various Hormones in Phytobase and HRT Heavy Cream Bases.

The release of United States Pharmacopeia Chapter <800> and the revisions to United States Pharmacopeia Chapter <795> (official November 1, 2023) indicates a changing regulatory climate and a trend towards increasingly high standards for the extension of beyond-use dates beyond the default recommended by the guidelines. Given the increased scrutiny and the additional requirements for establishing extended beyond-use dates, additional testing is required to help pharmacies provide the best formulations with scientifically robust data to support an extended beyond-use date for patient convenience. The objective of this study was to demonstrate the suitability of two vehicles, Phytobase and HRT Heavy, for compounded hormone therapy by evaluating the stability and antimicrobial effectiveness of the vehicles with common combinations of hormones.

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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
62
期刊介绍: The International Journal of Pharmaceutical Compounding (IJPC) is a bi-monthly, scientific and professional journal emphasizing quality pharmaceutical compounding. IJPC is the only publication that covers pharmaceutical compounding topics relevant and necessary to empower pharmacists to meet the needs of today"s patients. No other publication features hands-on, how-to compounding techniques or the information that contemporary pharmacists need to provide individualized care.
期刊最新文献
Acute Migraine Treatment with Timolol 0.5% Nasal Spray - Compounding Pharmacists Have an Important Role. Basics of Compounding: Tips and Hints, Part 4: Lollipops/Lozenges, Gummy Bears, Patches, Flavoring/Coloring, Sweeteners, and Packaging. Combination Therapy of Oral LDN and Topical Pentoxifylline, Rifampin, Clindamycin for Hidradenitis Suppurativa. Compounding Trade Association Issues Ketamine, Office Pay Best Practices APC Also Updated Position Statements on Constructive Transfer and Peptide Compounding. Extended Chemical and Microbial Stability of Various Hormones in Phytobase and HRT Heavy Cream Bases.
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