根治性前列腺切除术后拔除导管时的抗生素预防:文献系统回顾和荟萃分析。

Acta cirurgica brasileira Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI:10.1590/acb390424
Letícia Lourenço Dos Santos, Isabela de Almeida Fraga, Vitor Amaral de Almeida, Andressa Hellen Ribeiro Santos, Isabelle Matos Almeida, Tatiana Roberta Nascimento, Breno Cordeiro Porto, Carlo Camargo Passerotti, Everson Luiz de Almeida Artifon, Jose Pinhata Otoch, José Arnaldo Shiomi da Cruz
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引用次数: 0

摘要

目的:通过荟萃分析进行系统性文献综述,以确定拔除留置导尿管后使用抗生素预防是否会减少后发感染:使用关键词 "抗生素"、"前列腺切除术 "和 "导尿管",在PubMed、Embase、Cochrane、Google Scholar以及拉丁美洲和加勒比健康科学文献等数据库中进行了系统性文献综述:我们对三篇文章进行了荟萃分析,发现在拔除留置导尿管后,泌尿系统感染的风险略有显著降低(几率比-OR = 0.51;95%置信区间-95%CI 0.27-0.98;P = 0.04;I2 = 0%)。在是否存在菌尿方面没有发现差异(OR = 0.39;95% 置信区间-95%CI 0.12-1.24;P = 0.11;I2 = 73%):在我们的荟萃分析中,根治性前列腺切除术后拔除留置导尿管后使用抗生素预防尿路感染的情况明显减少。
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Antibiotics prophylaxis at the time of catheter removal after radical prostatectomy: a systematic review of the literature and meta-analysis.

Purpose: To conduct a systematic literature review with meta-analysis to identify whether antibiotic prophylaxis after removal of the indwelling urinary catheter reduces posterior infections.

Methods: A systematic literature review was conducted in the databases PubMed, Embase, Cochrane, Google Scholar, and Latin American and Caribbean Health Sciences Literature, using the keywords "antibiotics" AND "prostatectomy" AND "urinary catheter."

Results: Three articles were identified having the scope of our review, with 1,040 patients, which were subjected to our meta-analysis revealing a marginally significant decrease in the risk of urinary infection after indwelling urinary catheter removal (odds ratio-OR = 0.51; 95% confidence interval-95%CI 0.27-0.98; p = 0.04; I2 = 0%). No difference was found regarding the presence of bacteriuria (OR = 0.39; 95%CI 0.12-1.24; p = 0.11; I2 = 73%).

Conclusions: In our meta-analysis, there was a significant decrease in urinary tract infection with antibiotic prophylaxis after indwelling urinary catheter removal following radical prostatectomy.

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