{"title":"[秘鲁一家医院延误儿童结核病治疗的风险因素]。","authors":"Gabriela Cartolin P, Consuelo Luna M","doi":"10.32641/andespediatr.v94i6.4080","DOIUrl":null,"url":null,"abstract":"<p><p>Childhood tuberculosis (c-TB) continues to be one of the causes of morbidity and mortality in children, but there is still little information on the delay in the initiation of specific treatment.</p><p><strong>Objective: </strong>To determine the risk factors associated with delayed initiation of tuberculosis (TB) treatment in children under 15 years of age.</p><p><strong>Patients and method: </strong>Case-control study. Patients <15 years of age with a diagnosis of childhood pulmonary tuberculosis (c-PTB) with delayed treatment initiation >24 hours were included. Clinical and epidemiological variables were evaluated: age, gender, guardian's education, poverty level, origin, family history of TB, altered imaging findings, symptomatic, PPD >10mm, histology, bacteriology, resistance to treatment, and healthcare network. Bi and multivariate logistic regression analysis was performed, through which odds ratios were calculated.</p><p><strong>Results: </strong>We evaluated 116 patients with c-PTB with a delayed initiation of specific treatment of more than 24 hours, and 264 with start of treatment in the first 24 hours. The delay in anti-tuberculosis treatment had a median of 3 days with an interquartile range of 2 to 7 days. The patient with the least educated guardian had a delay in treatment initiation with an odds ratio of 7.47 (95%CI: 4.13 - 13.52). Belonging to the healthcare network A of Callao decreased the probability of having tuberculosis by 0.224 times (95%CI:0.11 - 0.46).</p><p><strong>Conclusion: </strong>Incomplete education level of the guardian is a risk factor associated with delayed initiation of c-PTB treatment in children under 15 years of age while belonging to the Callao healthcare network A is a factor that decreases the risk in the group under study.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"698-704"},"PeriodicalIF":0.5000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Risk factors in the delay of treatment of childhood tuberculosis in a Peruvian Hospital].\",\"authors\":\"Gabriela Cartolin P, Consuelo Luna M\",\"doi\":\"10.32641/andespediatr.v94i6.4080\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Childhood tuberculosis (c-TB) continues to be one of the causes of morbidity and mortality in children, but there is still little information on the delay in the initiation of specific treatment.</p><p><strong>Objective: </strong>To determine the risk factors associated with delayed initiation of tuberculosis (TB) treatment in children under 15 years of age.</p><p><strong>Patients and method: </strong>Case-control study. Patients <15 years of age with a diagnosis of childhood pulmonary tuberculosis (c-PTB) with delayed treatment initiation >24 hours were included. Clinical and epidemiological variables were evaluated: age, gender, guardian's education, poverty level, origin, family history of TB, altered imaging findings, symptomatic, PPD >10mm, histology, bacteriology, resistance to treatment, and healthcare network. Bi and multivariate logistic regression analysis was performed, through which odds ratios were calculated.</p><p><strong>Results: </strong>We evaluated 116 patients with c-PTB with a delayed initiation of specific treatment of more than 24 hours, and 264 with start of treatment in the first 24 hours. The delay in anti-tuberculosis treatment had a median of 3 days with an interquartile range of 2 to 7 days. The patient with the least educated guardian had a delay in treatment initiation with an odds ratio of 7.47 (95%CI: 4.13 - 13.52). Belonging to the healthcare network A of Callao decreased the probability of having tuberculosis by 0.224 times (95%CI:0.11 - 0.46).</p><p><strong>Conclusion: </strong>Incomplete education level of the guardian is a risk factor associated with delayed initiation of c-PTB treatment in children under 15 years of age while belonging to the Callao healthcare network A is a factor that decreases the risk in the group under study.</p>\",\"PeriodicalId\":72196,\"journal\":{\"name\":\"Andes pediatrica : revista Chilena de pediatria\",\"volume\":\"94 6\",\"pages\":\"698-704\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Andes pediatrica : revista Chilena de pediatria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32641/andespediatr.v94i6.4080\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Andes pediatrica : revista Chilena de pediatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32641/andespediatr.v94i6.4080","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
[Risk factors in the delay of treatment of childhood tuberculosis in a Peruvian Hospital].
Childhood tuberculosis (c-TB) continues to be one of the causes of morbidity and mortality in children, but there is still little information on the delay in the initiation of specific treatment.
Objective: To determine the risk factors associated with delayed initiation of tuberculosis (TB) treatment in children under 15 years of age.
Patients and method: Case-control study. Patients <15 years of age with a diagnosis of childhood pulmonary tuberculosis (c-PTB) with delayed treatment initiation >24 hours were included. Clinical and epidemiological variables were evaluated: age, gender, guardian's education, poverty level, origin, family history of TB, altered imaging findings, symptomatic, PPD >10mm, histology, bacteriology, resistance to treatment, and healthcare network. Bi and multivariate logistic regression analysis was performed, through which odds ratios were calculated.
Results: We evaluated 116 patients with c-PTB with a delayed initiation of specific treatment of more than 24 hours, and 264 with start of treatment in the first 24 hours. The delay in anti-tuberculosis treatment had a median of 3 days with an interquartile range of 2 to 7 days. The patient with the least educated guardian had a delay in treatment initiation with an odds ratio of 7.47 (95%CI: 4.13 - 13.52). Belonging to the healthcare network A of Callao decreased the probability of having tuberculosis by 0.224 times (95%CI:0.11 - 0.46).
Conclusion: Incomplete education level of the guardian is a risk factor associated with delayed initiation of c-PTB treatment in children under 15 years of age while belonging to the Callao healthcare network A is a factor that decreases the risk in the group under study.