针对心血管疾病的再生医学和纳米技术方法:最新进展与未来展望。

Muhammad Waseem Sajjad, Fatima Muzamil, Maida Sabir, Usman Ali Ashfaq
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摘要

再生医学是指以修复、替代或再生受损或患病组织或器官为重点的医学研究。心血管疾病(CVDs)是一个全球性的重大健康问题,也是许多国家的主要死亡原因。根据美国疾病控制和预防中心(CDC)的数据,在美国,每 34 秒就有一人死于心血管疾病,而根据世界卫生组织(WHO)的一份报告,心血管疾病是全球死亡的主要原因,每年约夺走 1,790 万人的生命。对于心血管疾病,目前有许多使用不同药物的传统治疗方法,但这些治疗方法并不充分。干细胞和纳米技术是再生医学治疗心血管疾病的前景广阔的研究领域。再生医学是推进和成功治疗各种疾病的革命性战略,旨在控制心血管疾病。这篇综述全面研究了使用不同类型的生物材料作为再生药物治疗心血管疾病的不同方法、不同干细胞在治疗中的重要性、纳米技术在治疗中的扩展作用、几种干细胞的施用、跟踪、成像和临床试验的最终观察等多个不同层面,并旨在让读者了解一些特定器官和疾病的新兴治疗应用,这些器官和疾病可能会在短期内从再生医学中得到改善。
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Regenerative Medicine and Nanotechnology approaches against Cardiovascular Diseases: Recent Advances and Future Prospective.

Regenerative medicine refers to medical research focusing on repairing, replacing, or regenerating damaged or diseased tissues or organs. Cardiovascular disease (CVDs) is a significant health issue globally and is the leading cause of death in many countries. According to the Centers for Disease Control and Prevention (CDC), one person dies every 34 seconds in the United States from cardiovascular diseases, and according to a World Health Organization (WHO) report, cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Many conventional treatments are available using different drugs for cardiovascular diseases, but these treatments are inadequate. Stem cells and nanotechnology are promising research areas for regenerative medicine treating CVDs. Regenerative medicines are a revolutionary strategy for advancing and successfully treating various diseases, intending to control cardiovascular disorders. This review is a comprehensive study of different treatment methods for cardiovascular diseases using different types of biomaterials as regenerative medicines, the importance of different stem cells in therapeutics, the expanded role of nanotechnology in treatment, the administration of several types of stem cells, their tracking, imaging, and the final observation of clinical trials on many different levels as well as it aims to keep readers up to pace on emerging therapeutic applications of some specific organs and disorders that may improve from regenerative medicine shortly.

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