使用新型烧蚀点阵式 2910 纳米掺铒氟化玻璃光纤激光器进行全脸和颈部换肤,治疗晚期光老化。

IF 2.2 3区 医学 Q2 DERMATOLOGY Lasers in Surgery and Medicine Pub Date : 2024-02-14 DOI:10.1002/lsm.23764
Taryn N. Murray MD, Jamie K. Hu MD, Paul M. Friedman MD
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引用次数: 0

摘要

目的:长期以来,烧蚀点阵激光一直被认为是面部换肤治疗晚期光老化的黄金标准。与传统的烧蚀激光器相比,这些激光器具有更高的安全性,但由于其点阵方式,通常需要更多的治疗疗程。在这项研究中,我们评估了一种新型 2910 nm 掺铒氟化玻璃光纤激光器(2910 nm 光纤激光器)(UltraClear;Acclaro Medical)用于治疗晚期光老化的全脸和颈部换肤:方法:22 名 44-80 岁的健康受试者因晚期面部光老化和褶皱而被纳入研究。所有受试者均接受了三次全脸和颈部多通道治疗,采用 2910 nm 光纤激光,治疗间隔为 6-8 周。研究人员要求受试者对治疗过程中的平均疼痛程度进行评分。在第三次治疗后的 90 天,受试者使用全球美学改善量表(GAIS)评估自己的改善情况,并评定对治疗的满意度。对治疗前和治疗后照片的评估由两名盲人医生审查员完成。审查人员被要求识别治疗前和治疗后的照片,并使用 GAIS 对改善程度进行评分:结果:15 位参与者完成了研究,6 位退出了研究(退出或失去随访)。受试者对整体外观的平均 GAIS 得分为 3.8。随访时受试者的平均满意度为 4.8。受试者的平均疼痛评分为 4.9 分。一位双盲医生评审员对受试者治疗后照片的识别正确率为 100%,而第二位双盲评审员对受试者治疗后照片的识别正确率为 93%。对数码照片的盲法评估显示,受试者的 GAIS 平均分为 3.2 分。治疗后的皮肤反应包括针尖状出血、红斑、水肿和软组织结痂,持续 5-7 天。没有出现感染、疤痕或色素沉着。有两例暂时性色素沉着:结论:使用新型 2910 nm 光纤激光器治疗晚期光老化和褶皱是安全有效的。与传统的点阵烧蚀激光相比,治疗过程中的不适感和停工期较短。
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Full-face and neck resurfacing with a novel ablative fractional 2910 nm erbium-doped fluoride glass fiber laser for advanced photoaging

Objectives

Ablative fractional lasers have long been considered the gold standard for facial resurfacing for advanced photoaging. These lasers offer an improved safety profile compared to traditional ablative lasers but typically require more treatment sessions given their fractional approach. In this study, we evaluate a new novel 2910 nm erbium-doped fluoride glass fiber laser (2910 nm fiber laser) (UltraClear; Acclaro Medical) for full-face and neck resurfacing for the treatment of advanced photoaging.

Methods

Twenty-two healthy subjects aged 44–80 years presenting for advanced facial photoaging and rhytides were enrolled in the study. All subjects received three full-face and neck, multipass treatments utilizing the 2910 nm fiber laser spaced 6–8 weeks apart. Subjects were asked to rate the average level of pain during the treatment. At 90 days following subjects' third treatment subjects evaluated their improvement using a Global Aesthetic Improvement Scale (GAIS) and rated their satisfaction with the treatment. Evaluation of pretreatment and posttreatment photos was completed by two blinded physician reviewers. Reviewers were asked to identify the pretreatment and posttreatment photographs and to rate the degree of improvement utilizing a GAIS.

Results

Fifteen participants completed the study; six were exited from the study (withdrew or lost to follow-up). The average subject GAIS score for overall appearance was 3.8. The average subject satisfaction level at follow-up was 4.8. The average subject pain score was 4.9. One blinded physician reviewer correctly identified 100% of subjects' posttreatment photographs, while the second blinded reviewer correctly identified 93%. Blinded evaluation of digital photographs revealed an average GAIS score of 3.2. Posttreatment skin responses included pin-point hemorrhage, erythema, edema, and soft tissue crusting lasting 5–7 days. There were no instances of infection, scarring or hypopigmentation. There were two instances of temporary hyperpigmentation.

Conclusions

Treatment with the novel 2910 nm fiber laser is safe and effective in treating advanced photoaging and rhytides. Three treatments produced moderate to marked improvement with high patient satisfaction and treatment was associated with less discomfort and downtime compared to conventional fractional ablative lasers.

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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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