Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity.

The American journal of Chinese medicine Pub Date : 2024-01-01 Epub Date: 2024-02-08 DOI:10.1142/S0192415X24500083
Fusheng Hao, Xinxin Deng, Xin Yu, Wen Wang, Wei Yan, Xi Zhao, Xiaofei Wang, Changcai Bai, Zhizhong Wang, Lu Han
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引用次数: 0

摘要

蒲公英(Taraxacum)是指蒲公英属(Taraxacum),该属植物作为药用植物的历史悠久,广泛分布于世界各地。在中国、中亚、欧洲和美洲,有超过 2500 种蒲公英属植物被记录为药用植物。传统上,它被用于解毒、利尿、保护肝脏、治疗各种炎症、抗菌等。我们以报道最典型的 Taraxacum officinale 为例,归纳了其化学成分,包括倍半萜、三萜、甾体、黄酮、糖及其衍生物、酚酸、脂肪酸和其他化合物,这也是其药理作用的物质基础。药理研究发现,蒲公英粗提取物和化学物质具有抗菌感染、抗炎、抗肿瘤、抗氧化、保护肝脏、控制血糖和血脂等功效。这些发现充分证实了之前描述的传统用途,并有助于解释其治疗应用。
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Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity.

Taraxacum refers to the genus Taraxacum, which has a long history of use as a medicinal plant and is widely distributed around the world. There are over 2500 species in the genus Taraxacum recorded as medicinal plants in China, Central Asia, Europe, and the Americas. It has traditionally been used for detoxification, diuresis, liver protection, the treatment of various inflammations, antimicrobial properties, and so on. We used the most typically reported Taraxacum officinale as an example and assembled its chemical makeup, including sesquiterpene, triterpene, steroids, flavone, sugar and its derivatives, phenolic acids, fatty acids, and other compounds, which are also the material basis for its pharmacological effects. Pharmacological investigations have revealed that Taraxacum crude extracts and chemical compounds contain antimicrobial infection, anti-inflammatory, antitumor, anti-oxidative, liver protective, and blood sugar and blood lipid management properties. These findings adequately confirm the previously described traditional uses and aid in explaining its therapeutic applications.

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