Stefano Spada, Sebastian Arlt, Daniela De Felice, Gary C W England, Marco Russo
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Twenty-three neutered dogs underwent a B-mode and CEUS examination of the prostate to acquire data about prostatic morphology and microcirculation. The prostate was imaged using a 5-7.5 MHz linear transducer and contrast was administered intravenously. Videoclips were analyzed by using Qontrast software and a postprocessing digital analysis tool (ImageJ) to measure perfusion peak intensity, time to peak, and vascularization ratio at the moment of the peak, which were then related to body weight, age, and time elapsed since orchiectomy. Correlation tests revealed higher vascularization in younger compared with older dogs (P < .05) and in smaller compared with larger dogs (P < .05). Time elapsed since orchiectomy (P > .05) did not affect prostatic perfusion. Contrast-enhanced ultrasound and the postprocessing analysis tool ImageJ allowed analysis of vascular perfusion in all dogs and have the potential to improve the diagnostic possibilities for andrological examination.</p>","PeriodicalId":23581,"journal":{"name":"Veterinary Radiology & Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Digital postprocessing analysis of prostatic perfusion in neutered dogs.\",\"authors\":\"Stefano Spada, Sebastian Arlt, Daniela De Felice, Gary C W England, Marco Russo\",\"doi\":\"10.1111/vru.13343\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>B-mode ultrasound is routinely performed to evaluate the prostate gland in neutered dogs, although, the detection of malignancies may be challenging. 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Videoclips were analyzed by using Qontrast software and a postprocessing digital analysis tool (ImageJ) to measure perfusion peak intensity, time to peak, and vascularization ratio at the moment of the peak, which were then related to body weight, age, and time elapsed since orchiectomy. Correlation tests revealed higher vascularization in younger compared with older dogs (P < .05) and in smaller compared with larger dogs (P < .05). Time elapsed since orchiectomy (P > .05) did not affect prostatic perfusion. 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引用次数: 0
摘要
B 型超声波是评估绝育犬前列腺的常规方法,但恶性肿瘤的检测可能具有挑战性。对比增强超声波(CEUS)已被证明可用于评估正常和患病犬的前列腺灌注情况,但对比超声波特征的判读仍可能是主观的。定量评估前列腺灌注的工具可提高结果的可靠性,从而及早发现绝育犬的前列腺肿瘤。本研究旨在评估后处理分析工具对健康绝育犬前列腺 CEUS 的适用性,提供定量测量结果,并研究个体特征对前列腺回流的影响。23 只绝育犬接受了前列腺 B 型和 CEUS 检查,以获取有关前列腺形态和微循环的数据。使用 5-7.5 MHz 线性传感器对前列腺进行成像,并静脉注射造影剂。使用Qontrast软件和后处理数字分析工具(ImageJ)对录像片段进行分析,测量灌注峰值强度、达到峰值的时间和峰值时刻的血管化比率,然后将其与体重、年龄和睾丸切除术后的时间联系起来。相关性测试表明,与年龄较大的狗相比,年龄较小的狗血管化程度更高(P .05),但这并不影响前列腺灌注。对比增强超声波和后处理分析工具 ImageJ 可以对所有狗的血管灌注情况进行分析,并有可能提高睾丸检查的诊断可能性。
Digital postprocessing analysis of prostatic perfusion in neutered dogs.
B-mode ultrasound is routinely performed to evaluate the prostate gland in neutered dogs, although, the detection of malignancies may be challenging. Contrast-enhanced ultrasound (CEUS) has shown to be useful for the assessment of prostatic perfusion in normal and diseased dogs, although the interpretation of contrast ultrasonographic features may still be subjective. A quantitative tool for evaluating prostatic perfusion might improve the reliability of the results in terms of early detection of prostate neoplasia in neutered dogs. The present study aimed to evaluate the applicability of a postprocessing analysis tool to CEUS of the prostate in healthy neutered dogs, to provide quantitative measurements, and to study the influence of individual characteristics on prostatic regression. Twenty-three neutered dogs underwent a B-mode and CEUS examination of the prostate to acquire data about prostatic morphology and microcirculation. The prostate was imaged using a 5-7.5 MHz linear transducer and contrast was administered intravenously. Videoclips were analyzed by using Qontrast software and a postprocessing digital analysis tool (ImageJ) to measure perfusion peak intensity, time to peak, and vascularization ratio at the moment of the peak, which were then related to body weight, age, and time elapsed since orchiectomy. Correlation tests revealed higher vascularization in younger compared with older dogs (P < .05) and in smaller compared with larger dogs (P < .05). Time elapsed since orchiectomy (P > .05) did not affect prostatic perfusion. Contrast-enhanced ultrasound and the postprocessing analysis tool ImageJ allowed analysis of vascular perfusion in all dogs and have the potential to improve the diagnostic possibilities for andrological examination.
期刊介绍:
Veterinary Radiology & Ultrasound is a bimonthly, international, peer-reviewed, research journal devoted to the fields of veterinary diagnostic imaging and radiation oncology. Established in 1958, it is owned by the American College of Veterinary Radiology and is also the official journal for six affiliate veterinary organizations. Veterinary Radiology & Ultrasound is represented on the International Committee of Medical Journal Editors, World Association of Medical Editors, and Committee on Publication Ethics.
The mission of Veterinary Radiology & Ultrasound is to serve as a leading resource for high quality articles that advance scientific knowledge and standards of clinical practice in the areas of veterinary diagnostic radiology, computed tomography, magnetic resonance imaging, ultrasonography, nuclear imaging, radiation oncology, and interventional radiology. Manuscript types include original investigations, imaging diagnosis reports, review articles, editorials and letters to the Editor. Acceptance criteria include originality, significance, quality, reader interest, composition and adherence to author guidelines.