食管创伤治疗的现状:系统回顾和比例荟萃分析。

IF 2.6 3区 医学 Diseases of the Esophagus Pub Date : 2024-06-01 DOI:10.1093/dote/doae007
Dimitrios Papaconstantinou, Emmanouil I Kapetanakis, Adam Mylonakis, Spyridon Davakis, Efstathios Kotidis, Evangelos Tagkalos, Ioannis Rouvelas, Dimitrios Schizas
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引用次数: 0

摘要

与创伤相关的食管损伤(TEIs)是一种罕见但致死率极高的疾病。创伤性食管损伤的表现多种多样,取决于损伤的部位和机制(钝伤与穿透伤),以及是否存在并发症。本系统综述和荟萃分析旨在明确影响 TEI 管理的临床特征。我们对 Medline、Embase 和 web of science 数据库中有关 TEI 患者的研究报告进行了系统性回顾。在对汇总数据进行荟萃分析时采用了随机效应模型。共纳入了 11 项研究,涉及 4605 名患者,总死亡率为 19%(95% 置信区间 (CI) 13-25%)。穿透性损伤的发生率高出34%(RR 0.66,95% CI 0.49-0.89,P = 0.01),主要发生在颈部。53%的病例采用了手术治疗(95% CI 32-73%),68%的患者伴有相关损伤(95% CI 43-94%)。就手术修复技术的选择而言,无论受伤部位如何,最常报告的是初级缝合修复术。27%的病例采用了术后引流,胸腔食管损伤的修复术后引流更为常见。估计依赖机械通气的时间为 5.91 天(95% CI 5.1-6.72 天),而在重症监护室的平均住院时间为 7.89 天(95% CI 7.14-8.65 天)。TEI是创伤患者中不常见的损伤,死亡率和发病率都很高。对随之而来的食管缺损进行开放式缝合修复是目前最常用的方法,而支架植入术则适用于经过严格筛选的病例。
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Current aspects in the management of esophageal trauma: a systematic review and proportional meta-analysis.

Trauma-related esophageal injuries (TEIs) are a rare but highly lethal condition. The presentation of TEIs is very diverse depending on the location and mechanism of injury (blunt vs. penetrating), as well as the presence or absence of concurrent injuries. The aim of the present systematic review and meta-analysis is to delineate the clinical features impacting TEI management. A systematic review of the Medline, Embase, and web of science databases was undertaken for studies reporting on patients with TEIs. A random effects model was employed in the meta-analysis of aggregated data. Eleven studies, incorporating 4605 patients, were included, with a pooled mortality rate of 19% (95% confidence interval (CI) 13-25%). Penetrating injuries were 34% more likely to occur (RR 0.66, 95% CI 0.49-0.89, P = 0.01), predominantly in the neck compartment. Surgery was employed in 53% of cases (95% CI 32-73%), with 68% of patients having associated injuries (95% CI 43-94%). In terms of choice of surgical repair technique, primary suture repair was most frequently reported, irrespective of injury location. Postoperative drainage was employed in 27% of the cases and was more common following repair of thoracic esophageal injuries. The estimated dependence on mechanical ventilation was 5.91 days (95% CI 5.1-6.72 days), while the length of stay in the intensive care unit averaged 7.89 days (95% CI 7.14-8.65 days). TEIs are uncommon injuries in trauma patients, associated with considerable mortality and morbidity. Open suture repair of ensuing esophageal defects is by large the most employed approach, while stenting may be indicated in carefully selected cases.

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来源期刊
Diseases of the Esophagus
Diseases of the Esophagus Medicine-Gastroenterology
自引率
7.70%
发文量
568
期刊介绍: Diseases of the Esophagus covers all aspects of the esophagus - etiology, investigation and diagnosis, and both medical and surgical treatment.
期刊最新文献
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