Tamanna Sultana , Emmanuel Eysseric , Pedro A. Segura , Paul A. Helm , Sonya Kleywegt , Chris D. Metcalfe
{"title":"作为五大湖水溶性污染物 \"预警 \"的定向和非定向分析被动采样法","authors":"Tamanna Sultana , Emmanuel Eysseric , Pedro A. Segura , Paul A. Helm , Sonya Kleywegt , Chris D. Metcalfe","doi":"10.1016/j.jglr.2024.102297","DOIUrl":null,"url":null,"abstract":"<div><p><span>The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in </span>positive ion<span> mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin<span> receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant<span>, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.</span></span></span></p></div>","PeriodicalId":54818,"journal":{"name":"Journal of Great Lakes Research","volume":"50 2","pages":"Article 102297"},"PeriodicalIF":2.4000,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Passive sampling with targeted and non-targeted analysis as an “Early Warning” of water-soluble contaminants in the Great Lakes\",\"authors\":\"Tamanna Sultana , Emmanuel Eysseric , Pedro A. Segura , Paul A. Helm , Sonya Kleywegt , Chris D. Metcalfe\",\"doi\":\"10.1016/j.jglr.2024.102297\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span>The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in </span>positive ion<span> mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin<span> receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant<span>, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.</span></span></span></p></div>\",\"PeriodicalId\":54818,\"journal\":{\"name\":\"Journal of Great Lakes Research\",\"volume\":\"50 2\",\"pages\":\"Article 102297\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Great Lakes Research\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0380133024000200\",\"RegionNum\":3,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Great Lakes Research","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0380133024000200","RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
Passive sampling with targeted and non-targeted analysis as an “Early Warning” of water-soluble contaminants in the Great Lakes
The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in positive ion mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.
期刊介绍:
Published six times per year, the Journal of Great Lakes Research is multidisciplinary in its coverage, publishing manuscripts on a wide range of theoretical and applied topics in the natural science fields of biology, chemistry, physics, geology, as well as social sciences of the large lakes of the world and their watersheds. Large lakes generally are considered as those lakes which have a mean surface area of >500 km2 (see Herdendorf, C.E. 1982. Large lakes of the world. J. Great Lakes Res. 8:379-412, for examples), although smaller lakes may be considered, especially if they are very deep. We also welcome contributions on saline lakes and research on estuarine waters where the results have application to large lakes.