作为五大湖水溶性污染物 "预警 "的定向和非定向分析被动采样法

IF 2.4 3区 环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES Journal of Great Lakes Research Pub Date : 2024-02-05 DOI:10.1016/j.jglr.2024.102297
Tamanna Sultana , Emmanuel Eysseric , Pedro A. Segura , Paul A. Helm , Sonya Kleywegt , Chris D. Metcalfe
{"title":"作为五大湖水溶性污染物 \"预警 \"的定向和非定向分析被动采样法","authors":"Tamanna Sultana ,&nbsp;Emmanuel Eysseric ,&nbsp;Pedro A. Segura ,&nbsp;Paul A. Helm ,&nbsp;Sonya Kleywegt ,&nbsp;Chris D. Metcalfe","doi":"10.1016/j.jglr.2024.102297","DOIUrl":null,"url":null,"abstract":"<div><p><span>The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in </span>positive ion<span> mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin<span> receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant<span>, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.</span></span></span></p></div>","PeriodicalId":54818,"journal":{"name":"Journal of Great Lakes Research","volume":"50 2","pages":"Article 102297"},"PeriodicalIF":2.4000,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Passive sampling with targeted and non-targeted analysis as an “Early Warning” of water-soluble contaminants in the Great Lakes\",\"authors\":\"Tamanna Sultana ,&nbsp;Emmanuel Eysseric ,&nbsp;Pedro A. Segura ,&nbsp;Paul A. Helm ,&nbsp;Sonya Kleywegt ,&nbsp;Chris D. Metcalfe\",\"doi\":\"10.1016/j.jglr.2024.102297\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span>The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in </span>positive ion<span> mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin<span> receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant<span>, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.</span></span></span></p></div>\",\"PeriodicalId\":54818,\"journal\":{\"name\":\"Journal of Great Lakes Research\",\"volume\":\"50 2\",\"pages\":\"Article 102297\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2024-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Great Lakes Research\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0380133024000200\",\"RegionNum\":3,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Great Lakes Research","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0380133024000200","RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

这项研究的目的是将被动采样与定向分析相结合,以量化已知的新关注污染物 (CEC),并通过非定向分析确定以前未知的水溶性化合物。极地有机化学综合采样器 (POCIS) 部署在加拿大安大略省汉密尔顿市污水处理厂处理过的污水中,以及汉密尔顿港的三个站点和安大略湖的近岸地点。有针对性的分析表明,在距离废水排放口最远的港口,药物、咖啡因和人造甜味剂的含量呈梯度分布,从废水中的最高含量到最低含量。目前使用的杀虫剂的估计浓度在海港中部最高。此外,还使用高分辨率四极杆飞行时间质谱分析了汇集的 POCIS 提取物,并使用模式识别应用程序对生成的精确质量数据进行了筛选。部署在海港中部的 POCIS 在正离子模式下检测到的特征数量最多,因此使用全球天然产品社会分子网络数据库对该站的精确质量数据进行了进一步评估。初步确定的新型 CEC 包括血管紧张素受体阻滞剂类药物。后续针对性分析证实,POCIS 中存在轮胎磨损化合物六甲氧基甲基苄胺 (HMMM)、煤焦油衍生化合物列匹定、抗惊厥药拉莫三嗪和止咳药右旋糖酐的代谢物。我们建议将这种方法作为大湖预警系统的一部分,以识别新出现的化学污染物威胁。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Passive sampling with targeted and non-targeted analysis as an “Early Warning” of water-soluble contaminants in the Great Lakes

The objective of this study was to integrate passive sampling with targeted analysis to quantify known contaminants of emerging concern (CECs) and, with non-targeted analysis. to identify previously unknown water-soluble compounds. Polar Organic Chemical Integrative Samplers (POCIS) were deployed in the treated effluent of a wastewater treatment plant serving the City of Hamilton, ON, Canada, as well as at three stations in Hamilton Harbour and at nearshore locations in Lake Ontario. Targeted analysis indicated that there was a gradient of pharmaceuticals, caffeine, and artificial sweeteners from highest levels in wastewater to lowest levels in the harbour furthest from the wastewater discharge. The estimated concentrations of current use pesticides were highest in the central part of the harbour. Pooled POCIS extracts were also analyzed using high-resolution quadrupole-time-of-flight mass spectrometry and the exact mass data generated were screened using a pattern recognition application. The greatest number of features were detected in positive ion mode from POCIS deployed in the central part of the harbour, and so exact mass data from this station were further evaluated using the Global Natural Products Social Molecular Networking data base. Novel CECs tentatively identified included pharmaceuticals from the angiotensin receptor blocker class. Follow-up targeted analysis confirmed that a tire wear compound, hexamethoxymethylmelamine (HMMM), the coal-tar derived compound, lepidine, the anticonvulsant, lamotrigine and a metabolite of a cough suppressant, dextrorphan, were present in POCIS. We propose that this approach be part of a Great Lakes Early Warning System to identify emerging threats from chemical contaminants.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Great Lakes Research
Journal of Great Lakes Research 生物-海洋与淡水生物学
CiteScore
5.10
自引率
13.60%
发文量
178
审稿时长
6 months
期刊介绍: Published six times per year, the Journal of Great Lakes Research is multidisciplinary in its coverage, publishing manuscripts on a wide range of theoretical and applied topics in the natural science fields of biology, chemistry, physics, geology, as well as social sciences of the large lakes of the world and their watersheds. Large lakes generally are considered as those lakes which have a mean surface area of >500 km2 (see Herdendorf, C.E. 1982. Large lakes of the world. J. Great Lakes Res. 8:379-412, for examples), although smaller lakes may be considered, especially if they are very deep. We also welcome contributions on saline lakes and research on estuarine waters where the results have application to large lakes.
期刊最新文献
Editorial Board Revisiting zooplankton as indicators in the Great Lakes: Which indicators detect temporal changes in the zooplankton community composition? Vertical distribution of Lake Superior cisco (Coregonus artedi) spawning aggregations and implications for population monitoring Cyanobacteria in cold waters: A study of nearshore cyanobacteria assemblages in Lake Superior Lake Superior fish community and fisheries, 2001–2022: An era of stability
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1