用于检测神经递质的光学传感器阵列

IF 3.4 Q2 CHEMISTRY, ANALYTICAL Analysis & sensing Pub Date : 2024-02-13 DOI:10.1002/anse.202300099
Palash Jana, Prof. Subhajit Bandyopadhyay
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引用次数: 0

摘要

神经递质对神经元之间的电化学通信至关重要。准确检测和监测神经递质对于了解人体神经系统的复杂性至关重要。尽管神经递质起着至关重要的作用,但它们在人体内与其他细胞成分一起以低浓度存在,这给精确检测和定量带来了挑战。虽然电化学检测是一项重要的技术,但其护理点诊断应用却受到复杂机器和样品制备的限制。为了解决这一局限性,人们开始探索神经递质的替代检测策略。本综述讨论了基于阵列的传感器的开发和原理,这些传感器旨在方便、快速地检测神经递质。此外,它还探讨了这些技术的实施和发展前景,为更好地了解和操纵人类神经系统描绘了美好的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Optical Sensor Arrays for the Detection of Neurotransmitters

Neurotransmitters are essential for electrochemical communication between neurons. Accurate detection and monitoring of neurotransmitters are crucial for comprehending the intricacies of the human nervous system. Despite their crucial role, neurotransmitters exist in the human body at low concentrations amidst other cellular components, posing challenges for their precise detection and quantification. While electrochemical detection stands as an important technique, its point-of-care diagnostic applications are constrained by complex machinery and sample preparation. To address this limitation, alternative detection strategies for neurotransmitters have been explored. This review discusses the development and principles of array-based sensors designed for facile and rapid detection of neurotransmitters. Moreover, it explores future prospects for the implementation and advancement of these techniques, envisioning a promising trajectory for improved understanding and manipulation of the human nervous system.

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