强化维生素 D3 的低脂乳制品对心血管风险因素人群焦虑、抑郁和压力的影响

P. Sharifan, H. Ghazizadeh, Susan Darroudi, Alireza Ghodsi, Sara Saffar Soflaei, Davoud Tanbacoochi, Mohammad Reza Fazl Mashhadi, Mohammad Amin Mohammadi, A. Dabagh, Sara Moazedi, Maryam Mohammadi Bajgiran, Gordon A. Ferns, H. Esmaily, Majid Ghayour-Mobarhan
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引用次数: 0

摘要

背景:维生素 D 缺乏症是一种世界性疾病,与多种健康相关问题有关。根据营养方法紫外线摄入量调查(SUVINA 研究),维生素 D 对心血管疾病(CVD)风险因素受试者的焦虑、抑郁和压力有潜在影响。研究方法这是一项四盲随机对照试验。受试者被随机分配到四组中的一组:强化低脂牛奶组(FM)、非强化低脂牛奶组(NFM)、强化低脂酸奶组(FY)和非强化低脂酸奶组(NFY)。FM组和FY组添加了1500 IU纳米胶囊维生素D3。在伊朗马什哈德进行了为期十周的试验后,对基线和试验后的人体测量参数以及抑郁、焦虑和压力评分进行了测量。研究结果共有 289 人(男性 143 人,女性 146 人)参加了研究,平均年龄(41.86±7.81)岁。有和没有心血管疾病风险因素的参与者在抑郁、焦虑和压力方面的得分没有统计学差异(P>0.05)。 根据牛奶和酸奶食用量进行的亚组分析也未发现统计学差异。结论含 1,500 IU 维生素 D 的强化低脂牛奶在十周内对改善抑郁、焦虑和压力没有影响。不过,建议进一步研究更高的维生素 D 剂量和更长的持续时间。
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Effect of Low-Fat Dairy Products Fortified with Encapsulated Vitamin D3 on Anxiety, Depression and Stress in People with Cardiovascular Risk Factors
Background: Vitamin D deficiency is a worldwide condition, which has been linked to a variety of health-related issues. Vitamin D can be beneficial to cardiovascular patients and those suffering from depression and anxiety, based on Survey of Ultraviolet Intake by Nutritional Approach (SUVINA study), ,showing the potential effects of vitamin D-fortified dairy products on anxiety, depression, and stress in subjects with cardiovascular disease (CVD) risk factors. Methods: It was a quadruple-blind randomized controlled trial. Individuals were randomly allocated to one of four groups: fortified low-fat milk (FM), non-fortified low-fat milk (NFM), fortified low-fat yogurt (FY), and non-fortified low-fat yogurt (NFY). FM and FY groups were fortified with 1500 IU nano-encapsulated vitamin D3. Anthropometric parameters as well as depression, anxiety, and stress scores were measured at baseline and after a ten-week trial in Mashhad, Iran. Results: Totally, 289 participants (143 men, 146 women) with a mean age of 41.86±7.81years were enrolled in the study. There was no statistical difference between the scores of depression, anxiety, and stress in participants with and without CVD risk factors (P>0.05).  No statistical difference was found in the subgroup analysis based on milk and yogurt consumption. Conclusions: Fortified low-fat milk containing 1,500 IU of vitamin D has no impact on improving depression, anxiety, and stress during ten weeks. However, further studies with higher vitamin D doses for a longer duration are recommended.
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来源期刊
Journal of Nutrition and Food Security
Journal of Nutrition and Food Security Medicine-Medicine (miscellaneous)
CiteScore
0.60
自引率
0.00%
发文量
61
审稿时长
16 weeks
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