气管插管与长期机械通气的心脏外科术后患者血管活性-肌张力评分降低有关

Thomas F. O'Shea MD , Lynze R. Franko MD , Dane C. Paneitz MD, MPH , Kenneth T. Shelton MD , Asishana A. Osho MD, MPH , Hugh G. Auchincloss MD, MPH
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引用次数: 0

摘要

目的我们试图量化气管切开术对有持续通气需求的心脏外科术后患者血流动力学稳定性的影响。方法对2018年至2022年期间接受气管切开术的有长期机械通气的心脏外科术后患者进行了回顾性、单中心和观察性分析。如果患者正在接受机械循环支持,或在气管切开术前 3 天发生了与之无关的重大并发症,则排除在外。使用血管活性-肌力评分对血管活性和肌力需求进行量化。结果确定了 61 名患者,其中 58 人符合纳入标准。与气管切开术前 3 天相比,气管切开术后 3 天的血管活性-肌力评分中位数从 3.35 天(四分位数间距为 0-8.79 天)降至 0 天(四分位数间距为 0-7.79 天)(P = 0.027)。这一趋势的图表显示,气管切开术时出现了一个明显的拐点。此外,气管切开术后,使用血管活性/肌注药物(术前 67.2% [n = 39] vs 术后 24.1% [n = 14];P < .001)和镇静剂(术前 62.1% [n = 36] vs 术后 27.6% [n = 16];P < .001)的患者人数减少。结论气管切开术后,长期机械通气的心脏手术患者血管活性-肌张力评分中位数显著降低。气管切开 3 天后,使用血管活性药物/肌注药物和镇静剂的患者人数也明显减少。这些数据表明,气管切开术对心脏手术后患者的血流动力学稳定性有积极影响,应考虑使用气管切开术促进术后恢复。
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Tracheostomy is associated with decreased vasoactive-inotropic score in postoperative cardiac surgery patients on prolonged mechanical ventilation

Objective

We sought to quantify the influence that tracheostomy placement has on the hemodynamic stability of postoperative cardiac surgery patients with persistent ventilatory requirements.

Methods

A retrospective, single-center, and observational analysis of postoperative cardiac surgery patients with prolonged mechanical ventilation who underwent tracheostomy placement from 2018 to 2022 was conducted. Patients were excluded if receiving mechanical circulatory support or if they had an unrelated significant complication 3 days surrounding tracheostomy placement. Vasoactive and inotropic requirements were quantified using the Vasoactive-Inotrope Score.

Results

Sixty-one patients were identified, of whom 58 met inclusion criteria. The median vasoactive-inotrope score over the 3 days before tracheostomy compared with 3 days after decreased from 3.35 days (interquartile range, 0-8.79) to 0 days (interquartile range, 0-7.79 days) (P = .027). Graphic representation of this trend demonstrates a clear inflection point at the time of tracheostomy. Also, after tracheostomy placement, fewer patients were on vasoactive/inotropic infusions (67.2% [n = 39] pre vs 24.1% [n = 14] post; P < .001) and sedative infusions (62.1% [n = 36] pre vs 27.6% [n = 16] post; P < .001). The percent of patients on active mechanical ventilation did not differ.

Conclusions

The median vasoactive-inotrope score in cardiac surgery patients with prolonged mechanical ventilation was significantly reduced after tracheostomy placement. There was also a significant reduction in the number of patients on vasoactive/inotropic and sedative infusions 3 days after tracheostomy. These data suggest that tracheostomy has a positive effect on the hemodynamic stability of patients after cardiac surgery and should be considered to facilitate postoperative recovery.

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