Efficacy and safety of cardiac sympathetic denervation for refractory ventricular arrhythmias: Experience of a Colombian hospital

Left or bilateral cardiac sympathetic denervation is employed as a final option for treating pharmacologically refractory ventricular arrhythmias of various etiologies. In this study, we share our experience with bilateral cardiac denervation. A total of 6 patients (mean age 73.8 years ± 6.5 years, mean LVEF 37 ± 8.3%), between 2021 and 2022, with sarcoidosis or ischemic heart disease underwent bilateral cardiac denervation due to electrical storm despite prior treatments. It was achieved complete resolution of ventricular arrhythmias in 100% of cases, with no recurrence of cardiac device shocks and no mortalities, neither cases of pneumothorax, Horner's syndrome, or other complications. Therefore, it was concluded that in this study, bilateral cardiac denervation was effective for treatment of refractory ventricular arrhythmias. Further larger studies are required to confirm these findings.